The efficiency of somatic cell nuclear transfer (SCNT) is low in the rabbit. So far, there have
been few live births reported and most clones died within the first 3 weeks after birth. It has …

Although cloning by somatic cell nuclear transfer (SCNT) has been achieved in various
mammalian species, its efficiency has been very low (Han et al. 2003 Theriogenology 59, 33 …

We previously demonstrated that the histone deacetylase inhibitor, trichostatin A (TSA),
improves the development of cat-cow interspecies somatic cell nuclear transfer (iSCNT) …

Many different approaches have been developed to improve the efficiency of animal cloning
by somatic cell nuclear transfer (SCNT), one of which is to modify histone acetylation levels …

Nuclear reprogramming is dependent upon a number of factors, including chromatin
organization and modification. Trychostatin A (TSA), a histone deacetylase inhibitor, was …

The low viability of embryos reconstructed by somatic cell nuclear transfer (SCNT) is
believed to be associated with epigenetic modification errors, and reduction of those errors …

Until now, the efficiency of animal cloning by somatic cell nuclear transfer (SCNT) has
remained low. Efforts to improve cloning efficiency have demonstrated a positive role of …

We studied the effects of trichostatin A (TSA), a histone deacetylase inhibitor, on the
development of bovine somatic cell nuclear transfer (SCNT) embryos by investigating (1) the …

It has been reported that 5 or 50 nM trichostatin A (TSA) treatment after somatic cell nuclear
transfer (NT) improves the success rate of mouse cloning (Kishigami et al. 2006 Biochem …

Somatic cell nuclear transfer (SCNT) efficiency is still low in rabbit. Previous studies
indicated that trichostatin A (TSA) treatment could improve cloning efficiency and term …