Shenqi Fuzheng injection facilitates skeletal muscle mitophagy mediated by the ubiquitination of HIF‐1α to ameliorate cancer‐associated fatigue

W Guo, S Liu, H Xia, J Luo, H Chen… - Journal of Cellular …, 2024 - Wiley Online Library
Cancer‐related fatigue (CRF) significantly impacts the quality of life of cancer patients. This
study investigates the therapeutic potential of Shenqi Fuzheng injection (SFI) in managing …

Deciphering the molecular mechanism of Yifei‐Sanjie pill in cancer‐related fatigue

Y Wu, S Zhou, D Pi, Y Dong, W Wang, H Ye… - Journal of …, 2023 - Wiley Online Library
Background. The incidence of cancer‐related fatigue (CRF) is increasing, but its lack of clear
pathogenesis makes its prevention and treatment difficult. Therefore, it is of great …

Network Pharmacology/Metabolomics‐Based Validation of AMPK and PI3K/AKT Signaling Pathway as a Central Role of Shengqi Fuzheng Injection Regulation of …

W Guo, S Liu, X Zheng, Z Xiao, H Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
Chinese herbal medicines have multiple targets and properties, and their use in
multidisciplinary cancer therapies has consequently received increasing attention. Here, we …

[HTML][HTML] Jian Pi Sheng Sui Gao (JPSSG) alleviation of skeletal myoblast cell apoptosis, oxidative stress, and mitochondrial dysfunction to improve cancer-related …

M Xiao, W Guo, C Zhang, Y Zhu, Z Li… - Annals of …, 2023 - ncbi.nlm.nih.gov
Background Jian Pi Sheng Sui Gao (JPSSG), a Chinese traditional herbal paste, possesses
certain efficacy in patients with cancer-related fatigue (CRF); however, its related …

[HTML][HTML] ShenQi FuZheng Injection ameliorates fatigue-like behavior in mouse models of cancer-related fatigue

G Zhu, B Zhang, F Jiang, L Zhao, F Liu - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Cancer-related fatigue (CRF) not only has a negative impact on work, daily activities and
social relationships, but also be a predictor of cancer patients' survival. And it has no FDA …

Yifei sanjie Pills Alleviate Chemotherapy‐Related Fatigue by Reducing Skeletal Muscle Injury and Inhibiting Tumor Growth in Lung Cancer Mice

Y Wu, D Pi, Y Chen, Q Zuo, L Lin… - Evidence‐Based …, 2022 - Wiley Online Library
Chemotherapy‐related fatigue (CRF), one of the most severe adverse effects observed in
cancer patients, has been theoretically related to oxidative stress, and antioxidant treatment …

[HTML][HTML] A novel PHD2 inhibitor acteoside from Cistanche tubulosa induces skeletal muscle mitophagy to improve cancer-related fatigue

S Zhang, F Gong, J Liu, T Liu, J Yang, J Hu - Biomedicine & …, 2022 - Elsevier
Objective To study whether ACT exerts anti-fatigue activity against CRF by inducing skeletal
muscle mitophagy via suppressing PHD2 to upregulate the HIF-1α/BNIP3 signaling …

A narrative review of cancer-related fatigue (CRF) and its possible pathogenesis

S Yang, S Chu, Y Gao, Q Ai, Y Liu, X Li, N Chen - Cells, 2019 - mdpi.com
Many cancer patients suffer from severe fatigue when treated with chemotherapy or
radiotherapy; however, the etiology and pathogenesis of this kind of fatigue remains …

Photobiomodulation therapy moderates cancer cachexia-associated muscle wasting through activating PI3K/AKT/FoxO3a pathway

Y Li, Y Chen, Y Liao, T Huang, Q Tang, C He, L Xu… - Apoptosis, 2024 - Springer
Cancer cachexia-associated muscle wasting as a multifactorial wasting syndrome, is an
important factor affecting the long-term survival rate of tumor patients. Photobiomodulation …

Baoyuan Jiedu decoction alleviates cancer-induced myotube atrophy by regulating mitochondrial dynamics through p38 MAPK/PGC-1α signaling pathway

D Wang, W Chen, Q Bi, X Zong, J Ruan, X Yin… - Frontiers in …, 2020 - frontiersin.org
Cancer cachexia is a multifactorial syndrome characterized by continuous body wasting and
loss of skeletal muscle. Impaired mitochondria function is closely associated with muscle …