Cytomegalovirus (CMV) resistance to ganciclovir occurs via mutations in the UL97 gene.
CMV DNA, from vitreous and blood specimens and from culture isolates from 87 patients …

Vitreous from patients with cytomegalovirus (CMV) retinitis was studied in order to identify
mutations in the CMV UL97 gene associated with clinical resistance to ganciclovir. Point …

Abstract Background The cytomegalovirus (CMV) UL97 gene can be sequenced either from
blood specimens directly amplified by polymerase chain reaction (PCR) or from culture …

Five AIDS patients with cytomegalovirus (CMV) retinitis who had received ganciclovir (GCV)
therapy were followed with serial blood sampling to detectchanges both in CMV load and in …

The purpose of this study was to determine the prevalence of UL97 resistance mutations in
cytomegalovirus (CMV) DNA amplified from the eyes of patients with AIDS and newly …

Background: Treatment of cytomegalovirus (CMV) diseases with protracted administration of
ganciclovir can promote the development of resistant CMV that is associated with a poor …

PURPOSE: To determine whether cytomegalovirus (CMV) retinitis that responded poorly to
intravenous ganciclovir therapy but responded to the ganciclovir implant was caused by …

Objective: To investigate the correlation between genotypic studies performed on blood
leukocytes and phenotypic results obtained from the corresponding blood viral isolates in …

Cytomegalovirus (CMV) retinitis is among the most common opportunistic infections in
patients with acquired immunodeficiency syndrome. In a prospective study of 210 patients …

Specific mutations in the UL97 region of human cytomegalovirus (HCMV) have been found
to confer resistance to laboratory-adapted strains subjected to ganciclovir selection. In this …