Background: Few studies have investigated the effects of conventional attention deficit-
hyperactivity disorder (ADHD) medication in the mouse 5-choice serial reaction time task (5 …

Nicotine can improve attentional performance in the rat as assessed by a modified five-
choice serial reaction time task (5-CSRTT), but it is not known if the effect is shared with …

Rationale Atomoxetine, reboxetine and methylphenidate all act at the noradrenaline
transporter (NAT) and atomoxetine and methylphenidate are licensed for the treatment of …

The behavioral effects of lesions of the prelimbic cortex (PL), mediodorsal nucleus of the
thalamus (MD), and anterior thalamic nuclei (ANT) were investigated in 2 attentional tasks in …

Dissociable effects of bilateral excitotoxic lesions of different regions of the rat neocortex,
including medial prefrontal and anterior cingulate cortices, were investigated in a five-choice …

Rationale Norepinephrine (NE) is involved in the control of sustained attention. Studies of
sustained attention in humans include measures of reaction time (RT) and RT variability …

Cognitive dysfunction, particularly attentional impairment, is a core feature of many
psychiatric disorders, yet is inadequately addressed by current treatments. Development of …

The role of norepinephrine (NE) in visuo-spatial attention remains poorly understood. Our
goal was to identify the attentional processes influenced by atomoxetine (ATX) injections, a …

A set of five tasks was designed to examine dynamic aspects of visual attention: selective
attention to color, selective attention to pattern, dividing and switching attention between …

Atypical attention orienting has been found to be impaired in many neuropsychological
disorders, but the underlying neural mechanism remains unclear. Attention can be oriented …