Colorectal cancer is a major cause of cancer-related death in many countries. Colorectal
carcinogenesis is a stepwise process which, from normal mucosa leads to malignancy …

Chronic inflammation characterizing patients with inflammatory bowel disease (IBD)
represents a major risk factor for the development of colorectal cancer. Mechanisms …

The connection between inflammation and tumorigenesis is well-established and in the last
decade has received a great deal of supporting evidence from genetic, pharmacological …

The inflammatory process plays a significant role in the development of colon cancer (CRC).
Intestinal cytokine networks are critical mediators of tissue homeostasis and inflammation …

The link between chronic inflammation and cancer has long been suspected, due to the
pioneering work of Rudolf Virchow over 150 years ago. Yet the causal relationship between …

Connection between inflammation and cancer is a rapidly developing field. Epidemiological
data suggests that inflammation along with distinct arms of host immune system plays a very …

Chronic inflammation is thought to be the leading cause of many human cancers including
colorectal cancer (CRC). Accordingly, epidemiologic and clinical studies indicate that …

Chronic inflammation can lead to the development of many diseases, including cancer.
Inflammatory bowel disease (IBD) that includes both ulcerative colitis (UC) and Crohn's …

Patients with ulcerative colitis and Crohn's disease are at increased risk for developing
colorectal cancer. To date, no known genetic basis has been identified to explain colorectal …

Colorectal cancer is one of the most commonly diagnosed cancers worldwide. Traditionally,
mechanisms of colorectal cancer formation have focused on genetic alterations including …