New ways for the preparation of heterocyclic gold (III) complexes

R Usón, J Vicente, MT Chicote - Journal of Organometallic Chemistry, 1981 - Elsevier
Abstract The reaction of 1, 2-dimethyl-2, 3, 4, 5-tetraphenylstannacyclopentadiene [(Ph 4 C
4) SnMe 2] with AuCl 3 (tht)(tht= tetrahydrothiophen) leads to the auracyclopentadiene …

Structure-activity relationships in a series of auranofin analogues showing remarkable antiproliferative properties

I Landini, L Massai, D Cirri, T Gamberi, P Paoli… - Journal of Inorganic …, 2020 - Elsevier
The antiproliferative properties of a series of structurally-related gold (I) and silver (I) linear
complexes inspired to the clinically established gold-based drug auranofin were …

Novel antitumor adamantane–azole gold (I) complexes as potential inhibitors of thioredoxin reductase

A Garcia, RC Machado, RM Grazul, MTP Lopes… - JBIC Journal of …, 2016 - Springer
Gold complexes that could act as antitumor agents have attracted great attention.
Heterocyclic compounds and their metal complexes display a broad spectrum of …

[HTML][HTML] Antiproliferative Homoleptic and heteroleptic phosphino silver (I) complexes: Effect of ligand combination on their biological mechanism of action

K Dammak, M Porchia, M De Franco, M Zancato… - Molecules, 2020 - mdpi.com
A series of neutral mixed-ligand [HB (pz) 3] Ag (PR3) silver (I) complexes (PR3= tertiary
phosphine,[HB (pz) 3]−= tris (pyrazolyl) borate anion), and the corresponding homoleptic [Ag …

Chemistry and biology of three representative gold (III) compounds as prospective anticancer agents

C Gabbiani, MA Cinellu, L Maiore, L Massai… - Inorganica Chimica …, 2012 - Elsevier
Aubipyc, ie [(bipydmb-H) Au (OH)][PF6](where bipydmb-H= deprotonated 6-(1, 1-
dimethylbenzyl)-2, 2′-bipyridine), Auoxo6, ie [(bipy2Me) 2Au2 (μ-O) 2][PF6] 2 (where …

Synthesis of gold (iii)← gold (i)–NHC through disproportionation: The role of gold (i)–NHC in the induction of apoptosis in HepG2 cells

A Nandy, T Samanta, S Mallick, P Mitra… - New Journal of …, 2016 - pubs.rsc.org
Starting from the proligand 2-[(6-methylpyridin-2-yl)] imidazo [1, 5-a] pyridin-4-ylium
hexafluorophosphate (1· PF6), three new complexes, viz.[Au (1) 2][PF6](2),[1/2AuCl2 …

Anticancer and antileishmanial in vitro activity of gold(I) complexes with 1,3,4‐oxadiazole‐2(3H)‐thione ligands derived from δ‐D‐gluconolactone

AV Espinosa, DS Costa, LG Tunes… - Chemical Biology & …, 2021 - Wiley Online Library
Four gold (I) complexes conceived as anticancer agents were synthesized by reacting [Au
(PEt3) Cl] and [Au (PPh3) Cl] with ligands derived from δ‐d‐gluconolactone. The ligands' …

[HTML][HTML] Recent developments in the medicinal applications of silver-NHC complexes and imidazolium salts

NA Johnson, MR Southerland, WJ Youngs - Molecules, 2017 - mdpi.com
Because of their great structural diversity and multitude of chemical properties, N-
heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently …

gold (I) bis (1, 2, 3-triazol-5-ylidene) complexes as promising selective anticancer compounds

JF Schlagintweit, CHG Jakob, NL Wilke… - Journal of Medicinal …, 2021 - ACS Publications
The synthesis and antiproliferative activity of Mes-and iPr-substituted gold (I) bis (1, 2, 3-
triazol-5-ylidene) complexes in various cancer cell lines are reported, showing nanomolar …

[HTML][HTML] Cationic gold (I) heteroleptic complexes bearing a pyrazole-derived N-heterocyclic carbene: syntheses, characterizations, and cytotoxic activities

H Sivaram, J Tan, HV Huynh - Dalton Transactions, 2013 - pubs.rsc.org
A series of cationic gold (I) heteroleptic complexes bearing the pyrazole-derived N-
heterocyclic carbene (NHC) FPyr (1, 2, 3, 4, 6, 7, 8, 9-octahydropyridazino [1, 2-a] indazolin …