Semaphorins comprise a family of molecules implicated in the guiding of growing axons and
neuronal progenitor cells. Further, semaphorins have been suggested to play a role in …

Semaphorins are a large family of developmental regulatory signals, characterized by
aberrant expression in human cancers. These molecules crucially control cell-cell …

Semaphorins are mainly known as guidance signals in development, acting through
receptors called Plexins. However, their role in cancer is rapidly emerging in the regulation …

Abstract Class 3 semaphorins (SEMA3) were first identified as glycoproteins that negatively
mediate neuronal guidance by binding to neuropilin and repelling neurons away from the …

Angiogenesis, the formation of new blood vessels from preexisting vasculature, is essential
for many physiological processes, and aberrant angiogenesis contributes to some of the …

Semaphorins are a large family of evolutionarily conserved morphogenetic molecules
originally identified for their repelling role in axonal guidance. Intriguingly, semaphorins …

The semaphorins are a large family of secreted and cell surface proteins that provide
attractive and repulsive cues for axon guidance during neuronal development. Semaphorins …

Semaphorins were discovered 11 years ago as molecular cues for axon guidance that are
conserved from invertebrates to humans. More than 20 semaphorin genes have been …

Semaphorins are extracellular signaling proteins that are essential for the development and
maintenance of many organs and tissues. The more than 20-member semaphorin protein …

Neuropilins (NRP) are receptors for the class 3 semaphorin (SEMA3) family of axon
guidance molecules and the vascular endothelial growth factor (VEGF) family of …