Simultaneous editing of GABA and GSH with Hadamard‐encoded MR spectroscopic imaging

KL Chan, G Oeltzschner, MG Saleh… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose To evaluate the feasibility of simultaneous MR spectroscopic imaging (MRSI) of
gamma‐aminobutyric acid (GABA) and glutathione (GSH) in the human brain using …

Simultaneous edited MRS of GABA, glutathione, and ethanol

MG Saleh, M Wang, M Mikkelsen, SCN Hui… - NMR in …, 2020 - Wiley Online Library
The aim of this work was to develop simultaneous edited MRS of γ‐aminobutyric acid
(GABA), glutathione (GSH), and ethanol (EtOH) using Hadamard encoding and …

Hadamard editing of glutathione and macromolecule‐suppressed GABA

G Oeltzschner, KL Chan, MG Saleh… - NMR in …, 2018 - Wiley Online Library
The primary inhibitory neurotransmitter γ‐aminobutyric acid (GABA) and the major
antioxidant glutathione (GSH) are compounds of high importance for the function and …

Simultaneous edited MRS of GABA and glutathione

MG Saleh, G Oeltzschner, KL Chan, NAJ Puts… - Neuroimage, 2016 - Elsevier
Edited MRS allows the detection of low-concentration metabolites, whose signals are not
resolved in the MR spectrum. Tailored acquisitions can be designed to detect, for example …

Simultaneous editing of GABA and glutathione at 7T using semi‐LASER localization

MG Saleh, M Mikkelsen, G Oeltzschner… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose To demonstrate simultaneous editing of the two most commonly edited and
overlapping signals, γ‐aminobutyric acid (GABA), and glutathione (GSH), with Hadamard …

Glutamate measurements using edited MRS

MG Saleh, A Prescot, L Chang, C Cloak… - Magnetic resonance …, 2024 - Wiley Online Library
Purpose To demonstrate J‐difference coediting of glutamate using Hadamard encoding and
reconstruction of Mescher‐Garwood‐edited spectroscopy (HERMES). Methods Density …

Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites

M Mikkelsen, DL Rimbault, PB Barker… - Neuroimage, 2019 - Elsevier
Accurate and reliable quantification of brain metabolites measured in vivo using 1 H
magnetic resonance spectroscopy (MRS) is a topic of continued interest. Aside from …

An evaluation of the reproducibility of 1H-MRS GABA and GSH levels acquired in healthy volunteers with J-difference editing sequences at varying echo times

JJ Prisciandaro, M Mikkelsen, MG Saleh… - Magnetic resonance …, 2020 - Elsevier
Recent advances in J-difference-edited proton magnetic resonance spectroscopy (1 H MRS)
data acquisition and processing have led to the development of Hadamard Encoding and …

Multi-vendor standardized sequence for edited magnetic resonance spectroscopy

MG Saleh, D Rimbault, M Mikkelsen, G Oeltzschner… - Neuroimage, 2019 - Elsevier
Spectral editing allows direct measurement of low-concentration metabolites, such as GABA,
glutathione (GSH) and lactate (Lac), relevant for understanding brain (patho) physiology …

HERMES: Hadamard encoding and reconstruction of MEGA‐edited spectroscopy

KL Chan, NAJ Puts, M Schär, PB Barker… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose To investigate a novel Hadamard‐encoded spectral editing scheme and evaluate
its performance in simultaneously quantifying N‐acetyl aspartate (NAA) and N‐acetyl …