Background Human enteroviruses, which are transmitted via a faecal‐oral route, have long
been associated with type 1 diabetes onset. Increased hygiene in the 20th century may now …

Type 1 diabetes (T1D) is an autoimmune disease characterized by the disturbance of
pancreatic insulin-producing cells, which results in hyperglycemia. The disease is …

Environmental factors, especially viruses, are involved in the initiation or the acceleration of
type 1 diabetes (T1D) pathogenesis. Epidemiological data strongly suggest that …

The pathogenesis of type 1 diabetes is widely believed to involve T cell-mediated
autoimmune processes directed against the insulin-producing beta cells in the pancreas …

The question if enteroviruses could cause beta-cell damage and type 1 diabetes has
become more and more relevant when recent studies have provided new evidence …

Common enterovirus infections appear to initiate or facilitate the pathogenetic processes
leading to type 1 diabetes, and sometimes also precipitate the clinical disease. It is not …

Type 1 (insulin-dependent) diabetes is a typical organ-specific autoimmune disease where
insulin-producing beta cells are destroyed by immune mediated mechanisms. The risk of the …

A complex interaction of genetic and environmental factors can trigger the immune-mediated
mechanism responsible for type 1 diabetes mellitus (T1DM) establishment. Environmental …

Background Enteroviruses have been implicated in the etiology of type 1 diabetes,
supported by immunoreactivity of enteroviral protein in islets, but presence of enteroviral …

Despite decades of research, the etiology of type 1 diabetes mellitus (DM) is unknown.
Several risk factors have been associated with type 1 DM, including viral infections, genetic …