Bio-design automation: software+ biology+ robots

DM Densmore, S Bhatia - Trends in biotechnology, 2014 - cell.com
Synthetic biology promises to usher in a new era of scientific innovation and discovery [1].
Applicationsof thistechnology are broad and diverse [2]. Although applications frequently …

Bio-design automation: Nobody said it would be easy

D Densmore - ACS synthetic biology, 2012 - ACS Publications
John F. Kennedy, Rice University, September 12, 1962 “Biology is complex.”“Biology is not
well understood enough to engineer.”“Biology is not ready for design software.” Sound …

IWBDA 2022: Toward a Modular Future of Synthetic Biology Driven by Bio-Design Automation

A Pandey - ACS Synthetic Biology, 2024 - ACS Publications
Synthetic biology has its roots in designing biological system behavior according to a
desired specification. For the last two decades, researchers have made scientific …

[PDF][PDF] TASBE: A tool-chain to accelerate synthetic biological engineering

J Beal, R Weiss, D Densmore, A Adler, J Babb… - Proceedings of the 3rd …, 2011 - Citeseer
There is a pressing need for design automation tools for synthetic biology systems.
Compared to electronic circuits, cellular information processing has more complex …

Needs and opportunities in bio-design automation: four areas for focus

E Appleton, D Densmore, C Madsen… - Current Opinion in …, 2017 - Elsevier
Bio-design automation (BDA) is an emerging field focused on computer-aided design,
engineering principles, and automated manufacturing of biological systems. Here we …

Computer-aided biodesign across scales

TE Gorochowski, JR Karr, F Parmeggiani… - … in Bioengineering and …, 2021 - frontiersin.org
Computer-aided design (CAD) has revolutionized many engineering fields, enabling the
quick exploration and testing of designs in silico, that minimizes the need for expensive and …

Genetic design automation: engineering fantasy or scientific renewal?

MW Lux, BW Bramlett, DA Ball, J Peccoud - Trends in biotechnology, 2012 - cell.com
The aim of synthetic biology is to make genetic systems more amenable to engineering,
which has naturally led to the development of computer-aided design (CAD) tools …

Levels of autonomy in synthetic biology engineering

J Beal, M Rogers - Molecular systems biology, 2020 - embopress.org
Engineering biological organisms is a complex, challenging, and often slow process. Other
engineering domains have addressed such challenges with a combination of …

Designing synthetic biology

CM Agapakis - ACS synthetic biology, 2014 - ACS Publications
Synthetic biology is frequently defined as the application of engineering design principles to
biology. Such principles are intended to streamline the practice of biological engineering, to …

Synthetic biology: from bacteria to stem cells

R Weiss - Proceedings of the 44th annual Design Automation …, 2007 - dl.acm.org
Synthetic biology is revolutionizing how we conceptualize and approach the engineering of
biological systems. Recent advances in the field are allowing us to expand beyond the …