Hepatocellular carcinoma (HCC) is a complex biological process and is often diagnosed at
advanced stages with no effective treatment options. With advances in tumor biology and …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths in
the world. Metabolic reprogramming is considered a new hallmark of cancer, but it remains …

Understanding genetic aberrations in cancer leads to discovery of new targets for cancer
therapies. The genomic landscape of hepatocellular carcinoma (HCC) has not been fully …

Primary liver cancer is one of the most commonly occurring cancers worldwide.
Hepatocellular carcinoma (HCC) represents the majority of primary liver cancer and is the …

Introduction: Hepatocellular carcinoma (HCC) is a significant problem globally because of
viral infections and the increasing incidence of obesity and fatty liver disease. However, it is …

Hepatocellular carcinoma is a substantial health concern. It is currently the third dominating
cause of mortality associated with cancer worldwide. The development of hepatocellular …

Hepatocellular carcinoma (HCC) is a major cause of cancer mortality worldwide.
Unresectable or metastatic HCC has a poor prognosis, and systemic cytotoxic …

Background Due to the frequent dysregulation of the PI3K/AKT/mTOR signaling pathway,
mTOR represents a suitable therapeutic target in hepatocellular carcinoma (HCC). However …

Abstract Deregulated PI3K/AKT/mTOR, Ras/Raf/MAPK, and c-Myc signaling pathways are of
prognostic significance in hepatocellular carcinoma (HCC). Sorafenib, the only drug …

Hepatocellular Carcinoma (HCC) continues to pose a substantial global health challenge
due to its high incidence and limited therapeutic options. In recent years, the Janus Kinase …