Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease destroying the insulin-
producing beta cells. Recently, stem cell therapy has been tested to treat T1D. In the present …

Regenerative and immunomodulatory properties of mesenchymal stem cells (MSCs) might
be applied for type 1 diabetes mellitus (T1DM) treatment. Thus, we proposed in vitro …

Mesenchymal stem cell (MSC) transplantation is a novel treatment for diabetes mellitus,
especially type 1 diabetes. Many recent publications have demonstrated the efficacy of MSC …

Background Long-term diabetes-associated complications are the major causes of morbidity
and mortality in individuals with diabetes. These diabetic complications are closely linked to …

Introduction Mesenchymal stromal/stem cells (MSCs) are multipotent cells that have the
ability to express and secrete a wide range of immunomodulatory molecules, cytokines …

Cell-based therapies offer considerable promise for prevention or cure of diabetes. We
explored the potential of autologous, self-renewing, mesenchymal stem cells (MSC) as a …

Aims To analyze therapeutic potential of the conditioned medium from adipose tissue-
derived stem cells (ASC) cultivated in 2D (CM-2D) and 3D (CM-3D) models, in mice with …

Abstract Background Type 1 diabetes (T1D) is a T-cell-mediated autoimmune disease
characterized by the irreversible destruction of insulin-producing β-cells in pancreatic islets …

Background Stem cell therapy holds great promise for the repair of injured tissues and
organs, and it is one of the most promising therapies for diabetes mellitus. Therefore, the …

Type 1 diabetes mellitus is a progressive disease caused by the destruction of pancreatic β-
cells, resulting in insulin dependency and hyperglycemia. While transplanted bone marrow …