[图书][B] Evaluating the Structural and Functional Consequences of Traumatic Joint Injury and Their Relation to NF-κB in a Non-invasive Model of Post-traumatic …

IM Berke - 2020 - search.proquest.com
Post-traumatic osteoarthritis (PTOA) is a painful and debilitating disease of the synovial joint,
characterized by degenerative changes to various joint tissues following traumatic joint …

[HTML][HTML] NF-κB-mediated effects on behavior and cartilage pathology in a non-invasive loading model of post-traumatic osteoarthritis

IM Berke, E Jain, B Yavuz, T McGrath, L Chen… - Osteoarthritis and …, 2021 - Elsevier
Objective This study aimed to examine the temporal activation of NF-κB and its relationship
to the development of pain-related sensitivity and behavioral changes in a non-invasive …

[HTML][HTML] Inflammation in joint injury and post-traumatic osteoarthritis

J Lieberthal, N Sambamurthy, CR Scanzello - Osteoarthritis and cartilage, 2015 - Elsevier
Inflammation is a variable feature of osteoarthritis (OA), associated with joint symptoms and
progression of disease. Signs of inflammation can be observed in joint fluids and tissues …

Early effects of acute joint injury, the beginnings of Post-Traumatic Osteoarthritis

D Leale - 2023 - escholarship.org
Osteoarthritis (OA) is a degenerative disease of the joints which is recently understood to
develop from inflammatory pathology. Injury to a joint is major risk factor for developing …

Robust Characterization of Non-Invasive Post-Traumatic Osteoarthritis Mouse Model

FUR Bhatti, YH Jeong, DG Kim, DD Brand, KA Hasty… - bioRxiv, 2021 - biorxiv.org
Objective Biochemical and molecular changes involved in the pathophysiology of post-
traumatic arthritis (PTOA) have not been fully understood. This study used non-invasive …

Post-traumatic arthritis: overview on pathogenic mechanisms and role of inflammation

L Punzi, P Galozzi, R Luisetto, M Favero… - RMD open, 2016 - rmdopen.bmj.com
Post-traumatic arthritis (PTA) develops after an acute direct trauma to the joints. PTA causes
about 12% of all osteoarthritis cases, and a history of physical trauma may also be found in …

Post-traumatic OA (PTOA): what have we learned to advance osteoarthritis?

F Watt - Current Opinion in Rheumatology, 2020 - ora.ox.ac.uk
Purpose of review: Current thinking in the study of post-traumatic osteoarthritis (PTOA) is
overviewed: the osteoarthritis which follows acute joint injury. The review particularly …

[PDF][PDF] Research Advances in the Development of Post-Traumatic Knee Osteoarthritis with Abnormal Mechanical Load, Inflammation, and Hemarthrosis

C Zhanga, W Wangb, X Lic, C Liaod… - Frontiers in Medical …, 2023 - francis-press.com
Knee injuries predominantly caused by anterior cruciate ligament (ACL) rupture and
meniscal harm are most frequent among young people and sports activities enthusiasts …

An evidence-based systematic review of human knee post-traumatic osteoarthritis (PTOA): timeline of clinical presentation and disease markers, comparison of knee …

CM Khella, R Asgarian, JM Horvath, B Rolauffs… - International Journal of …, 2021 - mdpi.com
Understanding the causality of the post-traumatic osteoarthritis (PTOA) disease process of
the knee joint is important for diagnosing early disease and developing new and effective …

Evidence for acute inflammation in the pathogenesis of different mouse models of post-traumatic osteoarthritis

AE Timkovich, K Santangelo, C Olver, J Moreno… - 2021 - mountainscholar.org
Post-traumatic osteoarthritis (PTOA) is a debilitating, degenerative condition affecting more
than 5.6 million people in the United States. Following injury to the knee, a person is 4.2 …