Studies of our group, first presented at a meeting of the Israel Atherosclerosis Society in
1973, indicated that atheromatosis might be the result of imbalance between the amounts of …

For most of its existence as a named entity, atherosclerosis has been defined principally in
morphological terms, as a widely prevalent lesion chiefly affecting large elastic and …

Macrophage-derived foam cells, which are characterized by massive deposition of
cytoplasmic cholesteryl esters, are the key cellular element in the early stage of …

To study the roles of modified low-density lipoprotein (LDL) and the molecular size of LDL in
atherogenesis, the following studies were carried out. Eight white male rabbits fed a …

It is shown that the LDL peroxide lipid products level is 1.6-4 times higher in patients with the
ischemic heart diseases (IHD) than in normal subjects. At the same time the LDL uptake by …

In the performed clinical and experimental investigation there were determined the
significance of lipoprotein modification in atherogenesis and the mechanisms of blood …

Modified forms of low density lipoprotein (LDL) are associated with increased atherogenicity.
Modified LDL, in comparison with native LDL, demonstrates enhanced cellular uptake by …

Circulating apolipoprotein B-containing lipoproteins, notably the low-density lipoproteins,
enter the inner layer of the arterial wall, the intima, where a fraction of them is retained and …

The growth of cellular components is one of the characteristic events in the development of
atherosclerosis. It is generally accepted that smooth muscle cells proliferate in …

Atherosclerosis is a multicausal disease characterized by the formation of cholesterol-
containing plaque in the pronounced intima nearest to the heart's elastic-type arteries that …