[HTML][HTML] Chemokines and chemokine receptors as promising targets in rheumatoid arthritis

MA Murayama, J Shimizu, C Miyabe, K Yudo… - Frontiers in …, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease that commonly causes inflammation
and bone destruction in multiple joints. Inflammatory cytokines, such as IL-6 and TNF-α, play …

Chemokine blockade: a new era in the treatment of rheumatoid arthritis?

JJ Haringman, PP Tak - Arthritis Res Ther, 2004 - Springer
Blockade of chemokines or chemokine receptors is emerging as a new potential treatment
for various immune-mediated conditions. This review focuses on the therapeutic potential in …

Role of chemokines and chemokine receptors in rheumatoid arthritis

NM Elemam, S Hannawi… - ImmunoTargets and …, 2020 - Taylor & Francis
Rheumatoid arthritis (RA) is one of the most prevalent autoimmune diseases and a
prototypic inflammatory disease, affecting the small joints of the hands and feet. Chemokines …

[HTML][HTML] Chemokines and chemokine receptors in arthritis

Z Szekanecz, A Vegvari, Z Szabo… - Frontiers in bioscience …, 2010 - ncbi.nlm.nih.gov
Chemokines are involved in leukocyte recruitment to inflammatory sites, such as the
synovial tissue in rheumatoid arthritis (RA). There is a structural and a functional …

Chemokine inhibition in inflammatory arthritis

PP Tak - Best Practice & Research Clinical Rheumatology, 2006 - Elsevier
Synovial inflammation in rheumatoid arthritis (RA) and other arthritides is, in part, dependent
on migration of inflammatory cells as well as retention of these cells at the site of …

Chemokines and chemokine receptors in rheumatoid arthritis

Z Szekanecz, J Kim, AE Koch - Seminars in immunology, 2003 - Elsevier
Chemokines are chemotactic cytokines involved in a number of pathological processes,
including inflammatory conditions. Chemokines play a role in the pathogenesis of various …

Chemokines in joint disease: the key to inflammation?

JJ Haringman, J Ludikhuize, PP Tak - Annals of the rheumatic diseases, 2004 - ard.bmj.com
Targeting chemokines and/or chemokine receptors appears to be an intriguing new
approach to treating chronic inflammatory disorders like rheumatoid arthritis, inflammatory …

[PDF][PDF] Chemokines and chemokine receptors as novel therapeutic targets in rheumatoid arthritis (RA): inhibitory effects of traditional Chinese medicinal components

X Chen, JJ Oppenheim, OM Howard - Cell Mol Immunol, 2004 - cmi.ustc.edu.cn
Chemokines are chemoattractant cytokines that direct the migration of leukocytes, and are
induced by inflammatory cytokines, growth factors and pathogenic stimuli (1). Chemokines …

Chemokines: their role in rheumatoid arthritis

CE Vergunst, PP Tak - Current rheumatology reports, 2005 - Springer
Chemokines are small proteins that can act on cells that express matching receptors. They
are best known for their role in migration of cells, especially immune cells. Chemo …

Successes and failures of chemokine-pathway targeting in rheumatoid arthritis

Z Szekanecz, AE Koch - Nature Reviews Rheumatology, 2016 - nature.com
Chemokines and chemokine receptors are involved in leukocyte recruitment and
angiogenesis underlying the pathogenesis of rheumatoid arthritis (RA) and other …