Prospective population studies in the primary prevention setting have shown that reduced
plasma levels of HDL cholesterol are associated with an increased risk of coronary disease …

Objective—In the reverse cholesterol transport pathway, high-density lipoprotein (HDL)
passes the endothelial cell barrier by mechanisms involving the scavenger receptor class B …

The accumulation of low-density lipoproteins (LDL) in the arterial wall plays a pivotal role in
the initiation and pathogenesis of atherosclerosis. Conversely, the removal of cholesterol …

The metabolism of high-density lipoproteins (HDL), which are inversely related to risk of
atherosclerotic cardiovascular disease, involves a complex interplay of factors regulating …

Evidence that low-density lipoprotein-cholesterol (LDL-C) causes cardiovascular disease
(CVD) is overwhelming. It has also been proven beyond all doubt that lowering the level of …

The inverse correlation between serum levels of high density lipoprotein (HDL) cholesterol
and the risk of coronary heart disease, the protection of susceptible animals from …

Multiple human population studies have established the concentration of high density
lipoprotein (HDL) cholesterol as an independent, inverse predictor of the risk of having a …

Alteration of endothelial cell functions, including reduced endothelial nitric oxide (NO)
availability, increased endothelial cell apoptosis, adhesion molecule/chemokine expression …

Vascular disease risk is inversely related to circulating levels of high-density lipoprotein
(HDL) cholesterol. However, the mechanisms by which HDL provides vascular protection …

Dysfunctional HDL is associated with coronary artery disease (CAD), but its effect on
inflammation in vascular smooth muscle cells (VSMCs) in atherosclerosis is unknown. We …