Modulation of high-density lipoprotein cholesterol metabolism and reverse cholesterol transport

M Hersberger, A Von Eckardstein - Atherosclerosis: Diet and Drugs, 2005 - Springer
Low high-density lipoprotein (HDL)-cholesterol (C) is an important risk factor for coronary
heart disease. In vitro, HDL exerts several potentially anti-atherogenic effects including …

High-density lipoprotein: vascular protective effects, dysfunction, and potential as therapeutic target

TF Lüscher, U Landmesser, A von Eckardstein… - Circulation …, 2014 - Am Heart Assoc
High-density lipoprotein (HDL) is a complex mixture of lipoproteins that is associated with
many minor proteins and lipids that influence the function of HDL. Although HDL is a …

Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses

L Yvan-Charvet, N Wang, AR Tall - … , thrombosis, and vascular …, 2010 - Am Heart Assoc
Atherosclerosis has been characterized as a chronic inflammatory response to cholesterol
deposition in arteries, but the mechanisms linking cholesterol accumulation in macrophage …

Advances in HDL: much more than lipid transporters

S Ben-Aicha, L Badimon, G Vilahur - International Journal of Molecular …, 2020 - mdpi.com
High Density Lipoprotein (HDL) particles, beyond serving as lipid transporters and playing a
key role in reverse cholesterol transport, carry a highly variable number of proteins, micro …

Regulation of signal transduction by HDL1

C Mineo, PW Shaul - Journal of lipid research, 2013 - ASBMB
High density lipoprotein (HDL) cholesterol has direct effects on numerous cell types that
influence cardiovascular and metabolic health. These include endothelial cells, vascular …

A role for the scavenger receptor, class B type I in high density lipoprotein dependent activation of cellular signaling pathways

A Al-Jarallah, BL Trigatti - Biochimica et Biophysica Acta (BBA)-Molecular …, 2010 - Elsevier
High density lipoprotein (HDL) levels are inversely proportional to the risk of coronary heart
disease. HDL mediates various anti-atherogenic pathways including reverse cholesterol …

[HTML][HTML] Introduction to lipids and lipoproteins

KR Feingold - Endotext [internet], 2024 - ncbi.nlm.nih.gov
Cholesterol and triglycerides are insoluble in water and therefore these lipids must be
transported in association with proteins. Lipoproteins are complex particles with a central …

Lack of inhibitory effect of HDL on TNFα-induced adhesion molecule expression in human aortic endothelial cells

WJ Zhang, R Stocker, MR McCall, TM Forte, B Frei - Atherosclerosis, 2002 - Elsevier
Monocyte adhesion to and transmigration across the endothelium are initiating steps in
atherogenesis. Cytokine-induced adhesion molecule expression in human umbilical vein …

High-density lipoprotein revisited: biological functions and clinical relevance

A von Eckardstein, BG Nordestgaard… - European heart …, 2023 - academic.oup.com
Previous interest in high-density lipoproteins (HDLs) focused on their possible protective
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …

Update on strategies to increase HDL quantity and function

D Duffy, DJ Rader - Nature Reviews Cardiology, 2009 - nature.com
Low levels of HDL cholesterol are a significant predictor of atherosclerotic cardiovascular
events. HDL is believed to protect against atherosclerosis by promoting reverse cholesterol …