Beside their key role in the regulation of cholesterol homeostasis, HDL exhibit antioxidant
and anti-inflammatory properties that participate to their general antiatherogenic effect. The …

Plasma high density lipoproteins (HDL) comprise a highly heterogeneous family of
lipoprotein particles, differing in density, size, surface charge, and lipid and protein …

Plasma levels of high-density lipoprotein (HDL) are strongly and inversely correlated with
atherosclerotic cardiovascular diseases. However, it is becoming clear that a functional HDL …

High-density lipoprotein (HDL) particles are highly complex polymolecular aggregates
capable of performing a remarkable range of atheroprotective functions. Considerable …

It is well recognised that increased levels of high density lipoprotein (HDL) protect against
atherosclerosis and correlate with improved prognosis for vascular disease associated …

Coronary heart disease (CHD) is a leading cause of death in western societies. In the last
few decades, a number of epidemiological studies have shown that a disproportion between …

Importantly, although liver and intestine ABCA1 may be the most critical for lipidating newly
synthesized lipid-free apoA-I, substantial additional cholesterol efflux to HDL occurs from …

High-density lipoproteins (HDL) contain approximately 25% of the cholesterol and< 5% of
the triglyceride in the plasma of human blood. However, the dynamic exchange of lipids and …

Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the
leading cause of death worldwide. It is well established that cholesterol ester-enriched foam …

Circulating levels of HDL cholesterol are inversely related to the risk of atherosclerosis, and
therapeutic increases in HDL reduce the incidence of cardiovascular events. A new study …