Faecal Volatile Organic Compound Analysis in De Novo Paediatric Inflammatory Bowel Disease by Gas Chromatography–Ion Mobility Spectrometry: A Case–Control …

E Vermeer, JZ Jagt, TK Stewart, JA Covington… - Sensors, 2024 - mdpi.com
The gut microbiota and its related metabolites differ between inflammatory bowel disease
(IBD) patients and healthy controls. In this study, we compared faecal volatile organic …

Faecal volatile organic compounds analysis using field asymmetric ion mobility spectrometry: Non-invasive diagnostics in paediatric inflammatory bowel disease

N Van Gaal, R Lakenman, J Covington… - Journal of breath …, 2017 - iopscience.iop.org
Abstract Background and Objectives: Inflammatory bowel disease (IBD), including Crohn's
disease (CD) and ulcerative colitis (UC), remains challenging to diagnose. Diagnostic work …

Faecal volatile organic compounds differ according to inflammatory bowel disease sub‐type, severity, and response to treatment in paediatric patients

S Belnour, R Slater, K Tharmaratnam… - United European …, 2024 - Wiley Online Library
Background Faecal volatile organic compounds (VOCs) differ with disease sub‐type and
activity in adults with established inflammatory bowel disease (IBD) taking therapy. Objective …

Optimized sampling conditions for fecal volatile organic compound analysis by means of field asymmetric ion mobility spectrometry

S Bosch, S el Manouni el Hassani… - Analytical …, 2018 - ACS Publications
Fecal volatile organic compounds (VOCs) are increasingly considered to be potential
noninvasive, diagnostic biomarkers for various gastrointestinal diseases. Knowledge of the …

Simultaneous assessment of urinary and fecal volatile organic compound analysis in de novo pediatric IBD

S el Manouni el Hassani, S Bosch, JPM Lemmen… - Sensors, 2019 - mdpi.com
Endoscopic evaluation is mandatory in establishing the diagnosis of pediatric inflammatory
bowel disease (IBD), but unfortunately carries a high burden on patients. Volatile organic …

[HTML][HTML] Wake up and smell the coffee: The potential of faecal volatile organic compounds in paediatric inflammatory bowel disease

E Vermeer, NKH de Boer… - United European …, 2024 - ncbi.nlm.nih.gov
In recent years, microbes and their metabolites are increasingly recognised as key players
in the pathogenesis of a wide range of gastrointestinal disorders, such as inflammatory …

[HTML][HTML] Gas Chromatography–Sensor System Aids Diagnosis of Inflammatory Bowel Disease, and Separates Crohn's from Ulcerative Colitis, in Children

R Slater, K Tharmaratnam, S Belnour… - Sensors (Basel …, 2024 - ncbi.nlm.nih.gov
The diagnosis of inflammatory bowel disease (IBD) in children and the need to distinguish
between subtypes (Crohn's disease (CD) and ulcerative colitis (UC)) requires lengthy …

Investigation of faecal volatile organic metabolites as novel diagnostic biomarkers in inflammatory bowel disease

I Ahmed, R Greenwood, B Costello… - Alimentary …, 2016 - Wiley Online Library
Background The aetiology of inflammatory bowel disease (IBD) remains poorly understood.
Recent evidence suggests an important role of gut microbial dysbiosis in IBD, and this may …

Differentiation between pediatric irritable bowel syndrome and inflammatory bowel disease based on fecal scent: proof of principle study

S Bosch, N van Gaal, RP Zuurbier… - Inflammatory Bowel …, 2018 - academic.oup.com
Background The diagnostic work-up of pediatric irritable bowel syndrome (IBS) and
functional abdominal pain–not otherwise specified (FAP-NOS) commonly includes invasive …

Metabolomic analysis of breath volatile organic compounds reveals unique breathprints in children with inflammatory bowel disease: a pilot study

N Patel, N Alkhouri, K Eng, F Cikach… - Alimentary …, 2014 - Wiley Online Library
Background Breath testing is becoming an important diagnostic method to evaluate many
disease states. In the light of rising healthcare costs, is important to develop a simple non …