Background Exposure to the environment of traditional farms can protect children from some
allergic disease. Due to this exposure, TLR 2 expression in these children is increased. TLR …

Background Peanut allergy is a life‐threatening condition; there is currently no cure. While
whole allergen extracts are used for specific immunotherapy for many allergies, they can …

Asthma is a chronic inflammatory airway disorder that is a subclass of IgE mediated
hypersensitivity. Cockroach allergy is one of the main reasons of asthma. German cockroach …

Type I immunoglobulin (Ig) E-mediated allergy, a state of hypersensitivity to allergens, is
becoming an important global health problem. In industrialized countries, more than 25% of …

Allergen-specific sublingual immunotherapy (SLIT) is well known as an effective and non-
invasive route to induce allergy desensitization. The goal of this study was to investigate …

Summary Background Ara h 2 and Ara h 6, co‐purified together in a 13–25 kD fraction (Ara
h 2/6; 20 kD fraction) on gel filtration chromatography, account for the majority of effector …

Peptide-based allergen immunotherapy is a novel alternative for conventional allergen
immunotherapy. Here, we have characterized the immunomodulatory potential of heteroclitic …

Purpose Developing experimental animal models that show clinical symptoms and methods
for quantitative and objective evaluation are important for understanding food allergies …

Specific immunotherapy is based on the administration of increasing doses of allergens to
allergic patients with the aim of inducing a state of antigen-specific unresponsiveness …

The cloning of allergen proteins and genetic engineering enabled the production of
vaccines that have well defined molecular, immunologic and biologic characteristics as well …