Cells utilize a diverse repertoire of cell surface and intracellular receptors to detect
exogenous or endogenous danger signals and even the changes of their microenvironment …

Nucleotide binding and oligomerization domain (NOD)-like receptor (NLR) initially appeared
in the public view as a cytoplasmic pathogen recognition receptor (PRR) that plays an …

Over the last decade, significant progress has been achieved in defining mechanisms
underlying NLR regulation of immune system function. However, several NLR family …

NLRX1 is a member of the NOD‐like receptor family, a set of pattern recognition receptors
associated with innate immunity. Interestingly, NLRX1 exists in somewhat of an exile from its …

Regulatory Nod-like receptors (NLRs) are a subgroup of the cytosolic NLR family of
pathogen recognition receptors (PRRs). These receptors can tune the innate immune …

NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization
domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating …

NOD‐like receptors (NLRs) are a family of intracellular sensors of microbial‐or danger‐
associated molecular patterns. Here, we report the identification of NLRX1, which is a new …

NLRP3, a member of nucleotide-binding domain-(NOD) like receptor family, can be found in
large varieties of immune and non-immune cells. Upon activation, the NLRP3, apoptosis …

The NOD like receptors (NLRs), a class of intracellular receptors that respond to pathogen
attack or cellular stress, have gained increasing attention. NLRC5, the largest member of the …

Chronic inflammation in tumor microenvironment plays an important role at different stages
of tumor development. The specific mechanisms of the association and its role in providing a …