OBJECTIVE: This study aimed to discover “signature pathways” that characterize biologic
processes, based on genes differentially expressed in the uterine cervix before and after …

Background Accurate identification of the women who will have spontaneous preterm birth
continues to be a great challenge. The use of cervical elastography for prediction of preterm …

The cervix is the essential gatekeeper for birth. Incomplete cervix remodeling contributes to
problems with delivery at or post-term while preterm birth is a major factor in perinatal …

To understand cervical ripening and especially the pathophysiology of cervical insufficiency,
it is important to know the cervical composition: the cervix is dominated by fibrous connective …

Remodeling of the cervix occurs in advance of labor both at term and at preterm birth.
Morphological characteristics associated with remodeling in rodents were assessed in …

Objective: To examine the relation between cervical dilatation and length and the risk of
spontaneous preterm birth, including its subtypes preterm labor and preterm premature …

Objective To quantitatively describe the evolution of ectocervical stiffness in normal
pregnancy. Methods The stiffness of ectocervical tissue was measured by using the …

Objective: To determine whether a soft cervix identified by shear-wave elastography
between 18 and 24 weeks of gestation is associated with increased frequency of …

A pivotal question in the physiology of gestation and parturition is how one relatively small
portion of the mammalian uterus, the cervix, functions at the anatomic and the molecular …

In normal pregnancy, the cervix functions as a protective mechanical barrier that must
remain tight and closed. Premature remodeling and consecutive shortening occur in many …