Background: Previous studies suggest that sex steroids influence colorectal cancer (CRC)
carcinogenesis. The oestrogen receptor β (ERβ) is the predominantly expressed ER in the …

Background The oestrogen receptor beta (ERβ) is the predominant oestrogen receptor in
the normal colon mucosa and has been reported to exert anti-proliferative and pro-apoptotic …

Gender differences in the incidence and behaviour of colon cancer suggest a hormonal
influence and epidemiological data suggest a protective effect for hormone replacement …

Background Estrogen receptor β (ERβ) is a potential tumor-suppressor gene in colorectal
cancer (CRC). This hypothesis is supported by clinical and laboratory observations. Aim In …

Oestrogen Receptor β (ERβ) may protect against prostate and mammary cell proliferation
and malignant transformation. Epidemiological studies indicate that oestrogens may reduce …

Oestrogen receptor β (ERβ) has been suggested to have anti‐proliferative and anti‐tumour
effects in breast and prostate cancer cells, but other studies have indicated its tumour …

Several strands of evidence indicate that oestrogens exert a protective role against the
development of colon cancer through indirect and direct effects on colonic epithelium …

BACKGROUND: A pivotal role of oestrogen receptor-beta has been suggested in colon
carcinogenesis in humans. However, few data are available on oestrogen receptor-beta in …

AIM: To determine the expression of estrogen receptor (ER) β in Chinese colorectal
carcinoma (CRC) patients. METHODS: ERβ expression in CRC was investigated by …

Background: Altered expression of estrogen receptors alpha and beta (ERα and ERβ) has
been hypothesized to play a role in carcinogenesis. However, little is known about the sex …