A prospective evaluation of endogenous sex hormone levels and colorectal cancer risk in postmenopausal women

N Murphy, HD Strickler, FZ Stanczyk… - Journal of the …, 2015 - academic.oup.com
Background: Postmenopausal hormone therapy use has been associated with lower
colorectal cancer risk in observational studies. However, the role of endogenous sex …

[HTML][HTML] Estrogen receptor beta as a prognostic factor in breast cancer patients: A systematic review and meta-analysis

W Tan, Q Li, K Chen, F Su, E Song, C Gong - Oncotarget, 2016 - ncbi.nlm.nih.gov
Background The prognostic role of estrogen receptor beta (ERβ) in early-stage breast
cancer is unclear. We performed a systematic review and meta-analysis to evaluate the …

[HTML][HTML] Expression of estrogen-related receptors in ovarian cancer and impact on survival

S Schueler-Toprak, F Weber, M Skrzypczak… - Journal of Cancer …, 2021 - Springer
Purpose This study further approaches the role of estrogen-related receptors (ERRs) in
ovarian cancer. Protein expression of ERRα, ERRβ and ERRγ in ovarian cancer was …

Impact of estrogen receptor-β expression on breast cancer prognosis: a meta-analysis

J Liu, H Guo, K Mao, K Zhang, H Deng… - Breast cancer research and …, 2016 - Springer
Estrogen receptor (ER)-β has been discovered for decades; however, its prognostic value in
breast cancer patients remains controversial. We aimed to evaluate the impact of ER-β …

[HTML][HTML] Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes

L Hases, R Indukuri, M Birgersson, T Nguyen-Vu… - Cancer letters, 2020 - Elsevier
Estrogen hormones protect against colorectal cancer (CRC) and a preventative role of
estrogen receptor beta (ERβ) on CRC has been supported using full knockout animals …

Estrogen receptor alpha negative breast cancer patients: estrogen receptor beta as a therapeutic target

GP Skliris, E Leygue, PH Watson, LC Murphy - The Journal of steroid …, 2008 - Elsevier
Clinical management of breast cancer is increasingly guided by assessment of tumor
phenotypic parameters. One of these is estrogen receptor (ER) status, currently defined by …

Estrogen and gastrointestinal malignancy

AM Hogan, D Collins, AW Baird, DC Winter - Molecular and cellular …, 2009 - Elsevier
The concept that E2 exerts an effect on the gastrointestinal tract is not new and its actions on
intestinal mucosa have been investigated for at least three decades. An attempt to …

Associations between ERα, ERβ, and AR Genotypes and Colon and Rectal Cancer

ML Slattery, C Sweeney, M Murtaugh, KN Ma… - … Biomarkers & Prevention, 2005 - AACR
Estrogen and androgens are thought to be involved in the etiology of colorectal cancer. We
evaluate genetic variants of the estrogen receptor genes (ERα and ERβ) and the androgen …

The favourable prognostic value of oestrogen receptor β immunohistochemical expression in breast cancer

L Nakopoulou, AC Lazaris… - Journal of clinical …, 2004 - jcp.bmj.com
Aims: Oestrogen receptor β (ERβ) is present in breast tumours, although its prognostic and
pathophysiological roles remain to be established. Methods: Standard …

[HTML][HTML] Correlation of mRNA for oestrogen receptor beta splice variants ERβ1, ERβ2/ERβcx and ERβ5 with outcome in endocrine-treated breast cancer

MPA Davies, PA O'Neill, H Innes… - Journal of …, 2004 - jme.bioscientifica.com
This study has been performed to test the hypothesis that different oestrogen receptor beta
(ERβ) splice variants may be important determinants of clinical parameters, including …