Role of alpha-fetoprotein in selection of patients with hepatocellular carcinoma waiting for liver transplantation: must we reconsider it?

Q Lai, AW Avolio, TM Manzia, S Agnes… - … journal of biological …, 2011 - journals.sagepub.com
Background Milan criteria (MC) represent the most commonly adopted criteria for the
selection of patients with hepatocellular carcinoma (HCC) waiting for liver transplantation …

The value of serum α-fetoprotein in predicting tumor recurrence after liver transplantation for hepatocellular carcinoma

X Xu, QH Ke, ZX Shao, J Wu, J Chen, L Zhou… - Digestive diseases and …, 2009 - Springer
Background Many patients with hepatocellular carcinoma (HCC) who undergo liver
transplantation (LT) subsequently develop tumor recurrence; this is the main factor affecting …

Prediction of recurrence of hepatocellular carcinoma after curative hepatectomy using preoperative Lens culinaris agglutinin‐reactive fraction of alpha‐fetoprotein

Y Saito, M Shimada, T Utsunomiya… - Hepatology …, 2012 - Wiley Online Library
Aim: Lens culinaris agglutinin A‐reactive fraction of α‐fetoprotein (AFP‐L3) status has been
reported to be an independent prognostic factor in patients with hepatocellular carcinoma …

Dynamic α-fetoprotein response and outcomes after liver transplant for hepatocellular carcinoma

KJ Halazun, RE Rosenblatt, N Mehta, Q Lai… - JAMA …, 2021 - jamanetwork.com
Importance Accurate preoperative prediction of hepatocellular carcinoma (HCC) recurrence
after liver transplant is the mainstay of selection tools used by transplant-governing bodies to …

Alpha‐fetoprotein and novel tumor biomarkers as predictors of hepatocellular carcinoma recurrence after surgery: a brilliant star raises again

Q Lai, F Melandro, RS Pinheiro… - … journal of hepatology, 2012 - Wiley Online Library
Alpha‐fetoprotein (AFP), des‐γ‐carboxy prothrombin (DCP), and lens culinaris agglutinin‐
reactive fraction of AFP (AFP‐L3) have been developed with the intent to detect …

Prognostic implications of alpha-fetoprotein and C-reactive protein elevation in hepatocellular carcinoma following resection (PACE): a large cohort study of 2770 …

KY Lin, QJ Chen, SC Tang, ZW Lin, JX Zhang… - BMC cancer, 2023 - Springer
Background Routine clinical staging for hepatocellular carcinoma (HCC) incorporates liver
function, general health, and tumor morphology. Further refinement of prognostic …

[HTML][HTML] Survival outcomes of liver transplantation for hepatocellular carcinoma in patients with normal, high and very high preoperative alpha-fetoprotein levels

WH She, ACY Chan, TT Cheung, CM Lo… - World Journal of …, 2018 - ncbi.nlm.nih.gov
AIM To investigate the impact of alpha-fetoprotein (AFP) on long-term recurrence rate and
overall survival and we also aimed to define the level of AFP leading to a higher risk of …

The dynamic changes of AFP from baseline to recurrence as an excellent prognostic factor of hepatocellular carcinoma after locoregional therapy: a 5-year …

Q Wang, B Liu, W Qiao, J Li, C Yuan, J Long… - Frontiers in …, 2021 - frontiersin.org
Background Although many studies have confirmed the prognostic value of preoperative
alpha-fetoprotein (AFP) in patients with hepatocellular carcinoma (HCC), the association …

The postresection alpha-fetoprotein in cirrhotic patients with hepatocellular carcinoma. An independent predictor of outcome

MA Allard, AS Cunha, A Ruiz, E Vibert… - Journal of …, 2014 - Elsevier
Background The postresection alpha-fetoprotein (AFP) in cirrhotic patients with
hepatocellular carcinoma (HCC) may predict overall survival (OS) and recurrence beyond …

Using serum α-fetoprotein for prognostic prediction in patients with hepatocellular carcinoma: what is the most optimal cutoff?

CY Hsu, PH Liu, YH Lee, CY Hsia, YH Huang, HC Lin… - PloS one, 2015 - journals.plos.org
Background and Aims The prognostic ability of α-fetoprotein (AFP) for patients with
hepatocellular carcinoma (HCC) was examined by using different cutoff values. The optimal …