In order to reduce the gastrointestinal side effect, of mefenamic acid, its carboxylic group
was condensed with the hydroxyl group of 1, 2, 3-trihydroxy propane 1, 3 …

Objective: The purpose of the study was to synthesize prodrugs of mefenamic acid, to be
used as Anti inflammatory drug with fewer adverse effects. Methods: The drug was …

This study deals with the synthesis, pharmacological activity, and kinetic studies of
mefenamic acid (MA) prodrugs of tyrosine and glycine. The synthesis involved a series of …

Mutual prodrugs consisting of mefenamic acid with menthol and thymol have been
synthesized as a gastrosparing NSAIDs, devoid of ulcerogenic side effects. The structures of …

Background: Non steroidal anti-inflammatory drugs are the most widely prescribed drugs to
manage pain and inflammatory conditions, but their long term use is associated with …

Glyceride derivatives ( and) of biphenyl acetic acid have been synthesized to reduce the
gastrointestinal toxicity associated with it and are tested for their ulcerogenicity, anti …

A novel mutual prodrug (MA-P) consisting of mefenamic acid (MA) and paracetamol (P) has
been synthesized as a gastrosparing NSAID, devoid of ulcerogenic side effects. The …

Gastrosparing novel prodrugs (MAM and MAT) synthesized consisted of mefenamic acid
(MA) with menthol (M) and thymol (T). Structural characterizations of synthesized esters …

The prodrugs (glyceride derivatives) 3a and 3b of diclofenac were prepared by reacting 1, 2,
3-trihydroxy propane-1, 3-dipalmitate/stearate with the acid chloride of diclofenac as …

Hydroxyethyl esters of diclofenac and mefenamic acid were prepared with the aim of
obtaining enzymatically labile prodrugs, and their stability was evaluated in aqueous buffer …