The evolving nature of neuropathic pain: individualizing treatment

HS Smith, CN Sang - European journal of Pain, 2002 - Elsevier
While it may be convenient to categorize neuropathic pain syndromes on the basis of
anatomical distribution or disease state (eg, diabetic neuropathy, radiculopathy, postherpetic …

Translational neuropathic pain research

N Attal, D Bouhassira - Pain, 2019 - journals.lww.com
The traditional translational approach in neuropathic pain research has mainly consisted to
date in translating basic findings from animal models of nerve injury to the clinic. Because of …

Dissecting out mechanisms responsible for peripheral neuropathic pain: implications for diagnosis and therapy

CJ Woolf - Life sciences, 2004 - Elsevier
Peripheral neuropathic pain, that clinical pain syndrome associated with lesions to the
peripheral nervous system, is characterized by positive and negative symptoms. Positive …

[HTML][HTML] Chronic neuropathic pain is more than a perception: Systems and methods for an integral characterization

DM Zolezzi, LM Alonso-Valerdi… - … & Biobehavioral Reviews, 2022 - Elsevier
The management of chronic neuropathic pain remains a challenge, because pain is
subjective, and measuring it objectively is usually out of question. However, neuropathic …

Pathophysiological mechanisms of neuropathic pain

C Leone, A Biasiotta, S La Cesa, G Di Stefano… - Future …, 2011 - Taylor & Francis
Neuropathic pain is a common problem in clinical practice and one that adversely affects
patients 'quality of life. Converging evidence from animal and human studies demonstrates …

[HTML][HTML] Neuropathic pain: challenges and opportunities

M van Velzen, A Dahan, M Niesters - Frontiers in Pain Research, 2020 - frontiersin.org
Chronic pain has a high prevalence in the Western World, where one in five individuals
suffers from chronic pain [1], that we define as frequent painful episodes lasting for at least 3 …

Shedding light on neuropathic pain: Current and emerging tools for diagnosis, screening, and quantification

A Hamdan, R Galvez, M Katati - SAGE Open Medicine, 2024 - journals.sagepub.com
Ensuring the proper management of neuropathic pain is a contemporary challenge for
professionals who care for patients with this type of pain. The estimated prevalence of …

Neuropathic pain

L Colloca, T Ludman, D Bouhassira, R Baron… - Nature reviews Disease …, 2017 - nature.com
Neuropathic pain is caused by a lesion or disease of the somatosensory system, including
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the …

Precision medicine in neuropathic pain

J Sachau, R Baron - Precision Medicine, 2023 - Springer
Neuropathic pain is a common chronic pain condition that is caused by a lesion or disease
of the somatosensory nervous system. The multitude of sensory negative and positive …

Mechanism-based therapy for neuropathic pain—a concept in danger?

A Binder, R Baron - Pain, 2015 - journals.lww.com
Solving the mystery of neuropathic pain and thereby improving the therapy for patients
suffering from pain have long been the goal of researchers around the world. However …