Randomized, double-blind, placebo-controlled trials on neuropathic pain treatment are
accumulating, so an updated review of the available evidence is needed. Studies were …

Neuropathic pain remains a significant unmet medical need. Several recommendations
have recently been proposed concerning pharmacotherapy, neurostimulation techniques …

Multiple drugs with different mechanisms of action have proven efficacy in relieving
neuropathic pain. Exhaustive treatment studies exist in patients with post herpetic neuralgia …

Purpose To explore the potential therapeutic strategies of different types of neuropathic pain
(NP) and to summarize the cutting-edge novel approaches for NP treatment based on the …

Neuropathic pain syndromes, ie, pain after a lesion or disease of the peripheral or central
nervous system, are clinically characterized by spontaneous pain (ongoing, paroxysms) and …

The development of new analgesics for neuropathic pain treatment is crucial. The failure of
promising drugs in clinical trials may be related to the over-reliance on reflex-based …

Neuropathic pain is caused by structural lesion leading to functional abnormalities in central
and peripheral nervous system. Neuropathic pain in itself is not always a disease, as it …

Neuropathic pain has been a very active and productive clinical research field over the last
15 years. Studies have concerned multiple aspects of these complex chronic pain …

Patients with neuropathic pain are heterogeneous in pathophysiology, etiology, and clinical
presentation. Signs and symptoms are determined by the nature of the injury and factors …

Classification of neuropathic pain has been based on disease entities, anatomical
localization, or histological observations. Over the past decade, there has been an explosion …