[HTML][HTML] Induction of apoptosis by berberine in hepatocellular carcinoma HepG2 cells via downregulation of NF-κB

M Li, M Zhang, Z Zhang, N Liu, X Han, Q Liu… - Oncology …, 2017 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is highly resistant to traditional chemotherapeutic
approaches, which causes difficulty in the development of effective drugs for the treatment of …

[HTML][HTML] Berberine induces apoptosis via the mitochondrial pathway in liver cancer cells

NKY Yip, WS Ho - Oncology reports, 2013 - spandidos-publications.com
Current chemotherapeutic strategies for liver cancer have limitations. Thus, the demand for
complementary medicine is warranted. We evaluated the antitumor potential of berberine, a …

Berberine induces selective apoptosis through the AMPK‑mediated mitochondrial/caspase pathway in hepatocellular carcinoma

X Yang, N Huang - Molecular Medicine Reports, 2013 - spandidos-publications.com
Advanced hepatocellular carcinoma (HCC) is insensitive to traditional chemotherapeutic
approaches, which causes difficulty in the development of novel agents for the treatment of …

Berberine induces cell cycle arrest in cholangiocarcinoma cell lines via inhibition of NF-κB and STAT3 pathways

N Puthdee, W Seubwai… - Biological and …, 2017 - jstage.jst.go.jp
Berberine is a natural compound found in several herbs. Anticancer activity of berberine was
reported in several cancers, however, little is known regarding the effects of berberine …

Berberine hydrochloride inhibits cell proliferation and promotes apoptosis of non-small cell lung cancer via the suppression of the MMP2 and Bcl-2/Bax signaling …

J Li, F Liu, S Jiang, J Liu, X Chen… - Oncology …, 2018 - spandidos-publications.com
Berberine, also known as berberine hydrochloride and isoquinoline alkaloid, is a major
alkaloid from Coptis chinensis. Berberine's extensive biological properties have previously …

[HTML][HTML] Mechanisms involved in the cytotoxic effects of berberine on human colon cancer HCT-8 cells

LN Xu, BN Lu, MM Hu, YW Xu, X Han, Y Qi, JY Peng - Biocell, 2012 - SciELO Argentina
Berberine, a constituent of some traditional Chinese medicinal plants, has been reported to
have cytotoxicity effects on different human cancer cell lines. There is no available …

Berberine induces cell death in human hepatoma cells in vitro by downregulating CD147

Q Hou, X Tang, H Liu, J Tang, Y Yang, X Jing… - Cancer …, 2011 - Wiley Online Library
The isoquinoline plant alkaloid berberine has anti‐tumor effects on a variety of carcinoma
cells, mainly through inhibition of cell proliferation, apoptosis induction and cell cycle arrest …

Berberine induces apoptosis through a mitochondria/caspases pathway in human hepatoma cells

JM Hwang, HC Kuo, TH Tseng, JY Liu, CY Chu - Archives of toxicology, 2006 - Springer
Berberine, a main component of Coptidis Rhizoma, is a plant alkaloid with a long history of
medicinal use in Chinese medicine. Berberine has indicated significant antimicrobial activity …

Exploring the active mechanism of berberine against HCC by systematic pharmacology and experimental validation

L Song, Y Luo, X Wang… - Molecular …, 2019 - spandidos-publications.com
Berberine (BBR) is the main component of Coptidis rhizoma, the dried rhizome of Coptis
chinensis and is a potential plant alkaloid used for the treatment of cancer due to its high …

Berberine induces apoptosis by suppressing the arachidonic acid metabolic pathway in hepatocellular carcinoma

J Li, O Li, M Kan, M Zhang, D Shao… - Molecular …, 2015 - spandidos-publications.com
Berberine (BBR) has been suggested as a potential candidate anticancer agent due to its
high anticancer activity and multiple mechanisms. In the present study, the inhibitory effect of …