Humans and other organisms have adapted to a consistent and predictable 24-h solar cycle,
but over the past∼ 130 years the widespread adoption of electric light has transformed our …

Substantial experimental evidence indicates a major role for the circadian system in mood
disorders. Additionally, proinflammatory cytokines have been proposed to be involved in the …

Simple Summary In the present study, we exposed mice to aberrant lighting system and
noticed anxiety-like behavior. These symptoms were ameliorated by oral administration of …

Background Bright light therapy (BLT) is widely used for treating Seasonal Affective Disorder
(SAD). However, the neural mechanisms underlying the therapeutic effects of BLT remain …

The disruption of circadian rhythms by environmental conditions can induce alterations in
body homeostasis, from behavior to metabolism. The light: dark cycle is the most reliable …

The circadian system maintains internal 24 h oscillation of behavior and physiology, and its
misalignment with external light-dark (LD) cycle results in negative health outcomes. In order …

Light has profound effects on mood regulation as exemplified in seasonal affective disorder
(SAD) and the therapeutic benefits of light therapy. However, the underlying neural …

Daily patterns of light exposure have become increasingly variable since the widespread
adoption of electrical lighting during the 20th century. Seasonal fluctuations in light …

Artificial light at night induces circadian disruptions and causes cognitive impairment and
mood disorders; yet very little is known about the neural and molecular correlates of these …

Bright light therapy is used as the primary treatment for seasonal affective disorder; however,
the mechanisms underlying its antidepressant effect are not fully understood. Previously, we …