Fungal pathogens are emerging as an important cause of human disease, and Candida
albicans is among the most common causative agents of fungal infections. Studying this …

Fungal pathogens are emerging as an important cause of human disease, and Candida
albicans is among the most common causative agents of fungal infections. Studying this …

Clustered regularly interspaced short palindromic repeat (CRISPR) methodology is not only
an efficient tool in gene editing but also an attractive platform to facilitate DNA, RNA, and …

Clustered regularly interspaced short palindromic repeat (CRISPR) methodology is not only
an efficient tool in gene editing but also an attractive platform to facilitate DNA, RNA, and …

Studying life-threatening fungal pathogens such as Candida albicans is of critical
importance, yet progress can be hindered by challenges associated with manipulating these …

For the fungal pathogen Candida albicans, genetic overexpression readily occurs via a
diversity of genomic alterations, such as aneuploidy and gain-of-function mutations, with …

Candida albicans is a pathogenic yeast that causes mucosal and systematic infections with
high mortality. The absence of facile molecular genetics has been a major impediment to …

ABSTRACT C lustered r egularly i nterspaced s hort p alindromic r epeat (CRISPR) and
CRISPR-associated gene 9 (CRISPR-Cas9) systems are used for a wide array of genome …

Candida albicans is an opportunistic fungal pathogen responsible for significant disease
and mortality. Absent complete mating and other convenient methods, dissection of its …

Candida albicans is a human fungal pathogen capable of causing life-threatening infections.
The ability to edit the C. albicans genome using CRISPR/Cas9 is an important tool …