Objective To determine the effect of inspiratory time and inspiratory flow pattern on albuterol
delivery by aerosol during mechanical ventilation. Design A ventilator was connected to a …

Successful bronchodilator therapy with a metered-dose inhaler (MDI) in intubated,
mechanically ventilated patients requires adequate delivery of aerosol to the lower …

Objective To provide an overview of aerosol drug delivery during mechanical ventilation in
the pediatric and adult populations. Data Sources Published articles and abstracts identified …

Background: Bronchodilators are increasingly being used in patients undergoing
mechanical ventilation. There are multiple factors that affect bronchodilator delivery during …

We determined the relative efficacy of two bronchodilator aerosol delivery methods in 18
intubated mechanically ventilated patients with airways obstruction. Two treatment arms …

The Nebulizer The Metered Dose Inhaler Differences during Mechanical Ventilation The
Ventilator-Patient Interface Breath Configurations The Airway The Environment The …

Aerosol delivery via a mechanical ventilator remains unregulated with no standards for drug
delivery to intubated patients. Bench models predicting drug delivery have not been …

Bronchodilators are frequently used in ICU patients, and are the most common medications
administered by inhalation during mechanical ventilation. The amount of bronchodilator that …

Using an in vitro model, we compared efficiencies of jet nebulizers and metered-dose
inhalers (MDI) with actuator devices to deliver albuterol in various conditions of mechanical …

BACKGROUND: The effectiveness of aerosol drug delivery during mechanical ventilation is
influenced by the patient, ventilator, and nebulizer variables. The impact of nebulizer type …