Effect of tidal volume and nebulizer type and position on albuterol delivery in a pediatric model of mechanical ventilation

A Berlinski, JR Willis - Respiratory Care, 2015 - rc.rcjournal.com
BACKGROUND: Optimization of factors affecting aerosol delivery during mechanical
ventilation in the pediatric population is important. We hypothesized that increasing the tidal …

Inhalation therapy in invasive and noninvasive mechanical ventilation

R Dhand - Current opinion in critical care, 2007 - journals.lww.com
Pressurized metered-dose inhalers of bronchodilator and corticosteroid aerosols are more
efficient and convenient to use than nebulizers for routine therapy in ventilated patients …

In-vitro/in-vivo comparison of inhaled salbutamol dose delivered by jet nebulizer, vibrating mesh nebulizer and metered dose inhaler with spacer during non-invasive …

A Hassan, R Salah Eldin… - Experimental lung …, 2017 - Taylor & Francis
Background: Patients receiving noninvasive ventilation (NIV) may benefit from medical
aerosol, but most guidance on dosing with different aerosol devices is limited to in-vitro …

Dose-response to bronchodilator delivered by metered-dose inhaler in ventilator-supported patients.

R Dhand, AG Duarte, A Jubran, JW Jenne… - American journal of …, 1996 - atsjournals.org
In nonintubated patients, metered-dose inhalers (MDIs) are accepted as the most
convenient, efficient, and cost effective method of administering inhaled bronchodilators …

How best to deliver aerosol medications to mechanically ventilated patients

R Dhand, VP Guntur - Clinics in chest medicine, 2008 - Elsevier
Pressurized metered-dose inhalers (pMDIs) and nebulizers are employed routinely for
aerosol delivery to ventilator-supported patients, but the ventilator circuit and artificial airway …

Bronchodilator delivery with metered-dose inhalers in mechanically-ventilated patients

R Dhand, MJ Tobin - European Respiratory Journal, 1996 - Eur Respiratory Soc
Metered-dose inhalers (MDIs) provide several advantages over nebulizers, including ease
of administration, decreased cost, reliability of dosing, and freedom from contamination …

How should aerosols be delivered during invasive mechanical ventilation?

R Dhand - Respiratory care, 2017 - rc.rcjournal.com
The delivery of aerosols to mechanically ventilated patients presents unique challenges and
differs from inhaled drug delivery in spontaneously breathing patients in several respects …

Nebulizer function during mechanical ventilation1-3

TG O'riordan, MJ Greco, RJ Perry… - Am Rev Respir Dis, 1992 - atsjournals.org
In the setting of mechanical ventilation, recent studies havecast doubt on the ability of
nebulizer systems to deliver adequate amounts of medication. Wetherefore studied …

Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study

J Dugernier, G Reychler, X Wittebole, J Roeseler… - Annals of intensive …, 2016 - Springer
Background Volume-controlled ventilation has been suggested to optimize lung deposition
during nebulization although promoting spontaneous ventilation is targeted to avoid …

In vitro study and semiempirical model for aerosol delivery control during mechanical ventilation

L Vecellio, C Guérin, D Grimbert, M De Monte… - Intensive care …, 2005 - Springer
The object of this study was to evaluate in vitro the influence of various ventilatory
parameters on the delivery of synchronized nebulization of terbutaline during mechanical …