A dose–response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult female offspring rats

SW Grande, AJM Andrade, CE Talsness, K Grote… - Toxicology, 2007 - Elsevier
Di (2-ethylhexyl) phthalate (DEHP) is used in numerous consumer products, mainly
imparting flexibility and durability to polyvinyl chloride (PVC) based plastics. It is a known …

A Dose-Response Study Following In Utero and Lactational Exposure to Di(2-ethylhexyl)phthalate: Effects on Female Rat Reproductive Development

SW Grande, AJM Andrade, CE Talsness… - Toxicological …, 2006 - academic.oup.com
Phthalates, a class of chemicals used as plasticizers, are economically important due to
several industrial applications. Di (2-ethylhexyl) phthalate (DEHP) is the most commonly …

A dose response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult male offspring rats

AJM Andrade, SW Grande, CE Talsness, C Gericke… - Toxicology, 2006 - Elsevier
The reproductive effects of in utero and lactational exposure to di-(2-ethylhexyl) phthalate
(DEHP) in adult male offspring rats were investigated. The selected endpoints included …

Effect of in utero exposure to di-(2-ethylhexyl) phthalate: distribution in the rat fetus and testosterone production by rat fetal testis in culture

T Stroheker, JF Regnier, J Lassurguere… - Food and chemical …, 2006 - Elsevier
DEHP is known to cause reproductive toxicity in rats, particularly during the neonatal period.
Pregnant and brood rats were treated by gavage with 750mg/kgb. w./day DEHP starting on …

Subchronic exposure to di (2-ethylhexyl) phthalate and diisononyl phthalate during adulthood has immediate and long-term reproductive consequences in female …

C Chiang, JA Flaws - Toxicological Sciences, 2019 - academic.oup.com
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a plasticizer used in a variety of consumer
products. This is concerning because DEHP is an endocrine disruptor and ovarian toxicant …

Effects of parenteral di‐(2‐ethylhexyl) phthalate (DEHP) on gonadal biochemistry, pathology, and reproductive performance of mice

DK Agarwal, WH Lawrence, JE Turner… - Journal of Toxicology …, 1989 - Taylor & Francis
Male and female mice were treated subcutaneously (sc) with 1–100 ml/kg of di‐(2‐
ethylhexyl) phthalate (DEHP) on d 1, 5, and 10 of the experiment and evaluated at d 21 for …

Di-(2-ethylhexyl) phthalate suppresses estradiol and ovulation in cycling rats

BJ Davis, RR Maronpot, JJ Heindel - Toxicology and applied pharmacology, 1994 - Elsevier
Di-(2-ethylhexyl) phthalate (DEHP) is a known reproductive toxicant and a carcinogen in
rodent animal models. DEHP may also be a reproductive toxicant in women. Its action in …

Di (2-ethylhexyl) phthalate (DEHP) alters proliferation and uterine gland numbers in the uteri of adult exposed mice

KA Richardson, PR Hannon, YJ Johnson-Walker… - Reproductive …, 2018 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is an endocrine-disrupting chemical that has
been shown to impair normal reproductive function in males and females. This study …

[HTML][HTML] Prenatal to peripubertal exposure to Di (2-ethylhexyl) phthalate induced endometrial atrophy and fibrosis in female mice

J Lee, SH Chang, YH Cho, JS Kim, H Kim… - Ecotoxicology and …, 2024 - Elsevier
Abstract Di (2-ethylhexy) phthalate (DEHP) is a widely used plasticizer that is ubiquitously
found in the environment. Using a mouse model, we investigated the impact of early life …

Diethylhexyl phthalate exposure impairs follicular development and affects oocyte maturation in the mouse

XF Zhang, LJ Zhang, L Li, YN Feng… - Environmental and …, 2013 - Wiley Online Library
Diethylhexyl phthalate (DEHP) is an estrogen‐like compound widely used as a commercial
plasticizer and present in medical devices, tubing, food containers and packaging. It is …