Parturition

R Smith - New England Journal of Medicine, 2007 - Mass Medical Soc
Preterm birth is associated with high rates of infant mortality and morbidity. This review
emphasizes that the onset of labor entails a molecular collaboration between the mother …

A systematic approach to the management of preterm labor

ER Norwitz, JN Robinson - Seminars in perinatology, 2001 - Elsevier
Preterm birth occurs in 7% to 12% of all deliveries, but accounts for over 85% of all perinatal
morbidity and mortality. Although the ability of obstetric care providers to identify women at …

The biological basis and prevention of preterm birth

GC Di Renzo, V Tosto, I Giardina - Best Practice & Research Clinical …, 2018 - Elsevier
The time of birth is a critical determinant of perinatal and long-term outcomes. Preterm birth
is still the first cause of infant mortality and morbidity; unfortunately, rates of preterm birth …

The molecular mechanisms of term and preterm labor: recent progress and clinical implications

JA Keelan, M Coleman, MD Mitchell - Clinical obstetrics and …, 1997 - journals.lww.com
Human parturition is characterized by a complex interplay of autocrine/paracrine factors and
signaling molecules within intrauterine tissues. The prevailing view is that factors produced …

Endocrinology of parturition

V Snegovskikh, JS Park… - … and Metabolism Clinics, 2006 - endo.theclinics.com
Reproductive success is critical for survival of the species. The timely onset of labor and
delivery is an important determinant of perinatal outcome. Preterm birth (defined as delivery …

Preterm labor: one syndrome, many causes

R Romero, SK Dey, SJ Fisher - Science, 2014 - science.org
Preterm birth is associated with 5 to 18% of pregnancies and is a leading cause of infant
morbidity and mortality. Spontaneous preterm labor, a syndrome caused by multiple …

Prevention of preterm birth: harnessing science to address the global epidemic

CE Rubens, Y Sadovsky, L Muglia… - Science translational …, 2014 - science.org
Preterm birth is a leading cause of infant morbidity and mortality worldwide, but current
interventions to prevent prematurity are largely ineffective. Preterm birth is increasingly …

Prevention of preterm delivery

HN Simhan, SN Caritis - New England Journal of Medicine, 2007 - Mass Medical Soc
Although preterm birth (at< 37 weeks' gestation) is sometimes indicated for the health of the
mother or her fetus, spontaneous preterm births occur as a consequence of spontaneous …

The preterm parturition syndrome and its implications for understanding the biology, risk assessment, diagnosis, treatment and prevention of preterm birth

F Gotsch, F Gotsch, R Romero, O Erez… - The Journal of …, 2009 - Taylor & Francis
The syndromic nature of spontaneous labour was a concept first proposed in 1994 [1]. It has
important implications for understanding the biology of preterm parturition, and also, setting …

The preterm parturition syndrome

R Romero, J Espinoza, JP Kusanovic… - … Journal of Obstetrics …, 2006 - Wiley Online Library
The implicit paradigm that has governed the study and clinical management of preterm
labour is that term and preterm parturition are the same processes, except for the gestational …