Aims/hypothesis In the present study, we investigated the consequences of adipose tissue
lipolytic inhibition on skeletal muscle substrate use in type 2 diabetic patients. Materials and …

The aim of the study was to evaluate an acute decrease in NEFA levels during an oral
glucose tolerance test and its effects on glucose tolerance, muscle glucose uptake and …

Suppression of lipolysis by acipimox is known to improve insulin-stimulated glucose
disposal, and this is an important phenomenon. The mechanism has been assumed to be …

Aims/hypothesis. Both patients with Type II (non-insulin-dependent) diabetes mellitus and
normoglycaemic, insulin resistant subjects were shown to have an increased lipid content in …

This study investigates the consequences of inhibition of adipose tissue lipolysis on skeletal
muscle substrate use. Ten subjects were studied at rest and during exercise and …

A lipolytic process in skeletal muscle has recently been demonstrated. However, the
physiological importance of this process is unknown. We investigated the role of skeletal …

Aims/hypothesis To test the hypothesis that adipose tissue lipolysis is enhanced in patients
with Type 2 diabetes mellitus, we examined the effect of exercise on regional adipose tissue …

Aims/hypothesis In order to test the hypothesis that disturbances in skeletal muscle fatty acid
metabolism with type 2 diabetes are not equally present in the upper and lower limbs, we …

Triglyceride accumulation in skeletal muscle is increased in subjects with insulin resistance.
Increased intracellular lipolysis from stored triglyceride may induce insulin resistance in …

Aims/hypothesis Disturbances in substrate source metabolism and, more particularly, in fatty
acid metabolism, play an important role in the aetiology and progression of type 2 diabetes …