Interleukin-10: cytokines in anti-inflammation and tolerance

A Howes, P Stimpson, P Redford, L Gabrysova… - … Frontiers: Regulation of …, 2014 - Springer
Abstract Interleukin (IL)-10 is an immunosuppressive cytokine produced by many cells of the
innate and adaptive immune response, including macrophages, dendritic cells, B cells, and …

Interleukin-10: biology, role in inflammation and autoimmunity

I Lalani, K Bhol, AR Ahmed - Annals of Allergy, Asthma & Immunology, 1997 - Elsevier
LEARNING OBJECTIVES: Reading this article will increase the readers' knowledge of the
biology of interleukin-10 (IL-10), an important cytokine. The survival of an organism and its …

Interleukin-10: an anti-inflammatory and immunosuppressive cytokine in the normal and pathological immune response

C Platzer - Current Medicinal Chemistry-Anti-Inflammatory & …, 2003 - ingentaconnect.com
The immunoregulatory cytokine IL-10 plays a key role in normal and pathological immune
responses due to its pleiotropic action on cells of the innate and specific immune system …

[PDF][PDF] Novel insights on interleukin-10 functions: A manipulative tool for the deviation of immune response and disease outcome

AH Bakiri, EÇ Mingomataj - EMJ Allergy Immunol, 2019 - emjreviews.com
It is known that IL-10 plays a critical role in the resolution of inflammation or tissue damage
and is the most widely studied anti-inflammatory cytokine, as discussed in different reviews …

[图书][B] Interleukin-10 in health and disease

S Fillatreau, A O'Garra - 2014 - Springer
The maintenance of immune homeostasis, as well as the induction and resolution of
immune responses is tightly controlled by the balanced provision of stimulatory and …

Interleukin-10 and the interleukin-10 receptor

KW Moore, R de Waal Malefyt… - Annual review of …, 2001 - annualreviews.org
Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of
T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on …

IL-10: a potential therapy for allergic inflammation?

M Pretolani, M Goldman - Immunology today, 1997 - cell.com
Abstract Interleukin 10 (IL-10) is currently regarded as a potential therapy for inflammatory
diseases involving T helper 1 (Th1)-type responses because of its ability to downregulate …

Functions and regulation of T cell-derived interleukin-10

C Neumann, A Scheffold, S Rutz - Seminars in immunology, 2019 - Elsevier
Abstract Interleukin (IL)-10 is an essential anti-inflammatory cytokine and functions as a
negative regulator of immune responses to microbial antigens. IL-10 is particularly important …

The multifaceted relationship between IL-10 and adaptive immunity: putting together the pieces of a puzzle

S Mocellin, F Marincola, CR Rossi, D Nitti… - Cytokine & growth factor …, 2004 - Elsevier
Interleukin-10 (IL-10) is a pleiotropic cytokine that modulates the function of several adaptive
immunity-related cells. Although generally considered an immunosuppressive molecule, IL …

Interleukin 10: an overview

D Rennick, D Berg, G Holland - Progress in growth factor research, 1992 - Elsevier
Since the original description of interleukin-10, a wealth of information concerning its
biological properties has been gathered. Studies in vitro have rapidly identified both …