Background: Surrogate markers for cardiovascular disease might be of great value in
observational research, clinical trials, and clinical practice. Carotid intima–media thickness …

Aims Measurement of change in carotid intima-media thickness (CIMT) has been proposed
as an alternative for the occurrence of cardiovascular (CV) events in the assessment of …

Background: To quantify the association between effects of interventions on carotid intima-
media thickness (cIMT) progression and their effects on cardiovascular disease (CVD) risk …

Background Carotid intima-media thickness (cIMT) is related to the risk of cardiovascular
events in the general population. An association between changes in cIMT and …

Carotid intima–media thickness (cIMT) has received interest as a predictor of cardiovascular
events in recent years. Use of cIMT in a clinical setting is limited by the variability in …

Cardiovascular (CV) disease is still the leading cause of death in the developed world,
despite the considerable progress in CV medical and surgical therapeutics. Many risk …

Background: Cardiovascular trials using clinical endpoints to assess efficacy typically
require followup of large numbers of participants for 3–5 years. This disadvantage has …

Aims Carotid intima media thickness (CIMT) predicts cardiovascular (CVD) events, but the
predictive value of CIMT change is debated. We assessed the relation between CIMT …

Aims Carotid intima media thickness (cIMT) is an intermediate phenotype of early
atherosclerosis that independently predicts vascular events. It is often suggested that cIMT …

Although atherosclerosis starts in early life, evidence on risk factors and atherosclerosis in
individuals aged< 45 years is scarce. Therefore, we studied the relationship between risk …