Grey and white matter abnormalities in minimal hepatic encephalopathy: a study combining voxel-based morphometry and tract-based spatial statistics

R Qi, LJ Zhang, J Zhong, T Zhu, Z Zhang, C Xu… - European …, 2013 - Springer
Objectives Low-grade cerebral oedema is considered to be pathognomonic of minimal
hepatic encephalopathy (MHE) in cirrhotic patients. The purpose of this study was to …

White matter microstructural disruption in minimal hepatic encephalopathy: a neurite orientation dispersion and density imaging (NODDI) study

QY Dong, JH Lin, Y Wu, YB Cao, MX Zhou, HJ Chen - Neuroradiology, 2023 - Springer
Purpose To evaluate the ability of neurite orientation dispersion and density imaging
(NODDI) for detecting white matter (WM) microstructural abnormalities in minimal hepatic …

Disturbance of thalamic metabolism and its association with regional neural dysfunction and cognitive impairment in minimal hepatic encephalopathy

LH Chen, JY Shi, TX Zou, L Zhang, Y Gou, Y Lin… - European Journal of …, 2020 - Elsevier
Purpose To conduct the first investigation on thalamic metabolic alterations in minimal
hepatic encephalopathy (MHE) and elucidate their association with intrinsic neural activity …

Focal cortical damage parallels cognitive impairment in minimal hepatic encephalopathy

C Montoliu, G Gonzalez-Escamilla, M Atienza, A Urios… - Neuroimage, 2012 - Elsevier
Little attention has been paid to cortical integrity in patients with minimal hepatic
encephalopathy (MHE), although cognitive functions affected in early stages of liver disease …

Altered regional homogeneity in the development of minimal hepatic encephalopathy: a resting-state functional MRI study

L Ni, R Qi, LJ Zhang, J Zhong, G Zheng, Z Zhang… - PloS one, 2012 - journals.plos.org
Background Little is known about how spontaneous brain activity progresses from non-
hepatic encephalopathy (non-HE) to minimal HE (MHE). The purpose of this study was to …

Identification of patients with and without minimal hepatic encephalopathy based on gray matter volumetry using a support vector machine learning algorithm

QF Chen, TX Zou, ZT Yang, HJ Chen - Scientific reports, 2020 - nature.com
Minimal hepatic encephalopathy (MHE) is characterized by diffuse abnormalities in cerebral
structure, such as reduced cortical thickness and altered brain parenchymal volume. This …

Disrupted thalamic resting-state functional connectivity in patients with minimal hepatic encephalopathy

R Qi, LJ Zhang, J Zhong, Z Zhang, L Ni, G Zheng… - European journal of …, 2013 - Elsevier
BACKGROUND AND PURPOSE: Little is known about the role of thalamus in the
pathophysiology of minimal hepatic encephalopathy (MHE). The purpose of this study was …

Evaluation of cognitivity, proinflammatory cytokines, and brain magnetic resonance imaging in minimal hepatic encephalopathy induced by cirrhosis and extrahepatic …

SK Yadav, A Goel, VA Saraswat… - Journal of …, 2016 - Wiley Online Library
Abstract Background and Aims Minimal hepatic encephalopathy (MHE) is the mildest form of
hepatic encephalopathy (HE) and is characterized by deficits in neurocognitive performance …

Microstructural brain abnormalities correlate with neurocognitive dysfunction in minimal hepatic encephalopathy: a diffusion kurtosis imaging study

JL Li, H Jiang, XD Zhang, LX Huang, SS Xie, L Zhang… - Neuroradiology, 2019 - Springer
Purpose To investigate the diffusion kurtosis imaging (DKI) in early minimal hepatic
encephalopathy (MHE) diagnosis and evaluate the correlations between changes in DKI …

T2* MRI of minimal hepatic encephalopathy and cognitive correlates in vivo

JY Liu, J Ding, D Lin, YF He, Z Dai… - Journal of Magnetic …, 2013 - Wiley Online Library
Purpose: To evaluate regional brain iron deposition in minimal hepatic encephalopathy
(MHE) patients using T2*‐weighted gradient‐echo imaging and to explore the relationship …