DNA methylation and hydroxymethylation and behavior
Environmentally sensitive molecular mechanisms in the brain, such as DNA methylation,
have become a significant focus of neuroscience research because of mounting evidence …
have become a significant focus of neuroscience research because of mounting evidence …
Hydroxymethylation and DNA methylation profiles in the prefrontal cortex of the non-human primate rhesus macaque and the impact of maternal deprivation on …
R Massart, M Suderman, N Provencal, C Yi, AJ Bennett… - Neuroscience, 2014 - Elsevier
Hydroxymethylcytosine (5hmC) is abundant in the brain, suggesting an important role in
epigenetic control of neuronal functions. In this paper, we show that 5hmC and 5 …
epigenetic control of neuronal functions. In this paper, we show that 5hmC and 5 …
Epigenetic mechanisms involved in the effects of stress exposure: focus on 5-hydroxymethylcytosine
hydroxymethylcytosine (5hmC) is a recently re-discovered transient intermediate in the
active demethylation pathway that also appears to play an independent role in modulating …
active demethylation pathway that also appears to play an independent role in modulating …
Gene-body 5-hydroxymethylation is associated with gene expression changes in the prefrontal cortex of depressed individuals
Hydroxymethylcytosine (5hmC) is a recently characterized epigenetic mark that is
particularly abundant in brain tissue and that regulates gene transcription. We have recently …
particularly abundant in brain tissue and that regulates gene transcription. We have recently …
New hope: the emerging role of 5-hydroxymethylcytosine in mental health and disease
Historically biomedical research has examined genetic influences on mental health but
these approaches have been limited, likely due to the broad heritability of brain-related …
these approaches have been limited, likely due to the broad heritability of brain-related …
Methylation on the mind
JD Flax, PD Soloway - Nature Neuroscience, 2011 - nature.com
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Methyl CpG Binding Domain Ultra‐Sequencing: a novel method for identifying inter‐individual and cell‐type‐specific variation in DNA methylation
Experience‐dependent changes in DNA methylation can exert profound effects on neuronal
function and behaviour. A single learning event can induce a variety of DNA modifications …
function and behaviour. A single learning event can induce a variety of DNA modifications …
Diversity of two forms of DNA methylation in the brain
DNA methylation 5-methylcytosine (5mC) predicts a compacting chromatin inaccessible to
transcription. The discovery of 5-hydroxymethylcytosine (5hmC), which is derived from 5mC …
transcription. The discovery of 5-hydroxymethylcytosine (5hmC), which is derived from 5mC …
[HTML][HTML] DNA modifications and neurological disorders
Mounting evidence has recently underscored the importance of DNA methylation in normal
brain functions. DNA methylation machineries are responsible for dynamic regulation of …
brain functions. DNA methylation machineries are responsible for dynamic regulation of …
5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging
DNA methylation dynamics influence brain function and are altered in neurological
disorders. 5-hydroxymethylcytosine (5-hmC), a DNA base that is derived from 5 …
disorders. 5-hydroxymethylcytosine (5-hmC), a DNA base that is derived from 5 …