H19 regulates the proliferation of bovine male germline stem cells via IGF‐1 signaling pathway

Q Lei, Q Pan, N Li, Z Zhou, J Zhang… - Journal of Cellular …, 2019 - Wiley Online Library
Self‐renewal and differentiation of male germline stem cells (mGSCs) provide the basic
function for continual spermatogenesis. Studies of in vitro culture of germline stem cells are …

The role of signaling pathways on proliferation and self-renewal of cultured bovine primitive germ cells

M Sahare, A Otomo, K Komatsu, N Minami… - … medicine and biology, 2015 - Springer
Purpose Gonocytes are primitive male germ cells residing in the neonatal testes and are
unipotent in nature, but also have pluripotent stem cell ability in mice under appropriate …

Characterization of immortalized dairy goat male germline stem cells (mGSCs)

H Zhu, J Ma, R Du, L Zheng, J Wu… - Journal of Cellular …, 2014 - Wiley Online Library
Male germline stem cells (mGSCs), in charge for the fertility in male testis, are the only kind
of adult stem cells that transmit genetic information to next generation, with promising …

Establishment and characterization of immortalized bovine male germline stem cell line

Q LEI, PAN Qin, Z Zhe, G LI, S CHEN, J HUA - Journal of integrative …, 2017 - Elsevier
Male germline stem cells (mGSCs) are unique adult germ cells with self-renewal potential
and spermatogenesis function in the testis. However, further studies are needed to establish …

IGF-1R Signaling Is Essential for the Proliferation of Cultured Mouse Spermatogonial Stem Cells by Promoting the G2/M Progression of the Cell Cycle

S Wang, X Wang, Y Wu, C Han - Stem cells and development, 2015 - liebertpub.com
Culture of mouse spermatogonial stem cells (mSSCs) contributes to understanding the
mechanisms of mammalian spermatogenesis. Several key growth factors such as GDNF …

p38 MAPK pathway is essential for self‐renewal of mouse male germline stem cells (mGSC s)

Z Niu, H Mu, H Zhu, J Wu, J Hua - Cell proliferation, 2017 - Wiley Online Library
Objectives Male germline stem cells (mGSC s), also called spermatogonial stem cells (SSC
s), constantly generate spermatozoa in male animals. A number of preliminary studies on …

Optimization of the conditions of isolation and culture of dairy goat male germline stem cells (mGSC)

H Zhu, C Liu, M Li, J Sun, W Song, J Hua - Animal reproduction science, 2013 - Elsevier
Male germline stem cells (mGSC) reside in the basement of seminiferous tubules of the
testis and have the capacity of self-renewal and differentiation into sperm throughout the life …

The effects of IGF-1 on mouse spermatogenesis using an organ culture method

J Yao, H Zuo, J Gao, M Wang, D Wang, X Li - Biochemical and biophysical …, 2017 - Elsevier
Currently available organ culture methods can induce the differentiation of spermatogonial
stem cells (SSCs) to spermatids in vitro, but the percentages of haploid cells and elongated …

Pluripotency of mouse spermatogonial stem cells maintained by IGF‐1‐dependent pathway

YH Huang, CC Chin, HN Ho, CK Chou… - The FASEB …, 2009 - Wiley Online Library
Recent studies indicate that neonatal spermatogonia! stem cells (SSCs) possess
pluripotency. However, the mechanisms that regulate the pluripotent differentiation capacity …

MiR‐302 enhances the viability and stemness of male germline stem cells

H Zhu, L Zheng, L Wang, F Tang… - Reproduction in domestic …, 2018 - Wiley Online Library
Contents MicroRNAs were reported to be able to regulate mGSCs' self‐renewal through
post‐transcriptional inhibition of gene expression. miR‐302 worked as one important …