Introduction Enteroviruses are among the most common viruses causing a huge number of
acute and chronic infections leading to high economic costs. Novel nontoxic antivirals that …

Enteroviruses, members of the Picornaviridae family, are non‐enveloped and single‐
stranded RNA viruses responsible for several human diseases. During infection, these …

Like other enteroviruses, enterovirus 71 (EV71) relies on phosphatidylinositol 4-kinase IIIβ
(PI4KB) for genome RNA replication. However, how PI4KB is recruited to the genome …

The filoviruses, Ebola and Marburg, utilize a multifaceted mechanism for assembly and
budding of infectious virions from mammalian cells. Growing evidence not only …

Enterovirus 71 (EV71), a member of the Picornaviridae family, is found in Asian countries
where it causes a wide range of human diseases. No effective therapy is available for the …

Enteroviruses support cell-to-cell viral transmission prior to their canonical lytic spread of
virus. Poliovirus (PV), a prototype for human pathogenic positive-sense RNA enteroviruses …

Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are the most common causes
of hand, foot, and mouth disease. Severe EV-A71 and CV-A16 infections may be associated …

The cellular mRNA decay protein AUF1 acts as a restriction factor during infection by
picornaviruses, including poliovirus, coxsackievirus, and human rhinovirus. AUF1 …

The phosphatidylinositol-4 kinase IIIβ (PI4KB)/oxysterol-binding protein (OSBP) family I
pathway serves as an essential host pathway for the formation of viral replication complex …

Enteroviruses modify several cellular functions to ensure efficient replication. However,
some of these alterations can trigger a defensive apoptotic host-cell program. To prevent …