Epigenetic modulation upon exposure of lung fibroblasts to TiO2 and ZnO nanoparticles: alterations in DNA methylation

NA Patil, WN Gade, DD Deobagkar - International journal of …, 2016 - Taylor & Francis
Titanium dioxide (TiO2) and zinc oxide (ZnO) nanoparticles (NPs) are promising candidates
for numerous applications in consumer products. This will lead to increased human …

Different effects of titanium dioxide nanoparticles instillation in young and adult mice on DNA methylation related with lung inflammation and fibrosis

Y Ma, Y Guo, H Ye, K Huang, Z Lv, Y Ke - Ecotoxicology and Environmental …, 2019 - Elsevier
Wide use of titanium dioxide nanoparticles (TiO 2 NPs) as white pigments induces
unintentionally release in environment which increases concerns about their adverse health …

Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines

M Pogribna, NA Koonce, A Mathew, B Word… - …, 2020 - Taylor & Francis
Nanoscale titanium dioxide (TiO2) is manufactured in wide scale, with a range of
applications in consumer products. Significant toxicity of TiO2 nanoparticles has, however …

Titanium dioxide nanoparticles induce size-dependent cytotoxicity and genomic DNA hypomethylation in human respiratory cells

Y Ma, Y Guo, S Wu, Z Lv, Q Zhang, Y Ke - RSC advances, 2017 - pubs.rsc.org
The widespread use of titanium dioxide nanoparticles (TiO2 NPs) is gradually increasing the
risk of exposure to these potentially hazardous materials. Although numerous health effects …

Cyto-genotoxic and DNA methylation changes induced by different crystal phases of TiO2-np in bronchial epithelial (16-HBE) cells

M Ghosh, D Öner, RC Duca, SM Cokic, S Seys… - Mutation Research …, 2017 - Elsevier
With the increase in use of TiO 2-np, a better understanding of their safety is important. In the
present study the effect of different crystal phases of TiO 2-np (anatase, rutile and anatase …

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes

MI Sierra, L Rubio, GF Bayón, I Cobo… - …, 2017 - Taylor & Francis
Humans are increasingly exposed to nanoparticles and, although many of their
physiological effects have been described, the molecular mechanisms underlying them are …

From the cover: zinc oxide nanoparticles-induced reactive oxygen species promotes multimodal cyto-and epigenetic toxicity

SR Choudhury, J Ordaz, CL Lo… - Toxicological …, 2017 - academic.oup.com
In this study we evaluated and correlated the cytotoxic effects of zinc oxide nanoparticles
(ZnO-NPs) to the epigenetic modifications, using human embryonic kidney (HEK-293) cells …

Changes in DNA methylation in mouse lungs after a single intra-tracheal administration of nanomaterials

AM Tabish, K Poels, HM Byun, K Luyts, AA Baccarelli… - PloS one, 2017 - journals.plos.org
Aims This study aimed to investigate the effects of nanomaterial (NM) exposure on DNA
methylation. Methods and Results Intra-tracheal administration of NM: gold nanoparticles …

In vivo epigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles

X Lu, IR Miousse, SV Pirela, JK Moore, S Melnyk… - …, 2016 - Taylor & Francis
Evidence continues to grow on potential environmental health hazards associated with
engineered nanomaterials (ENMs). While the geno-and cytotoxic effects of ENMs have been …

Effect of titanium dioxide nanoparticles on DNA methylation of human peripheral blood mononuclear cells

M Malakootian, A Nasiri, AR Osornio-Vargas… - Toxicology …, 2021 - academic.oup.com
The aim of the current study was to investigate the effect of well-characterized TiO2
nanoparticles on DNA methylation of peripheral blood mononuclear cells (PBMCs) in vitro …