Complementing cancer photodynamic therapy with ferroptosis through iron oxide loaded porphyrin-grafted lipid nanoparticles
Nanomaterials that combine multimodality imaging and therapeutic functions within a single
nanoplatform have drawn extensive attention for molecular medicines and biological …
nanoplatform have drawn extensive attention for molecular medicines and biological …
Iron-based nanoparticles for MR imaging-guided ferroptosis in combination with photodynamic therapy to enhance cancer treatment
Q Chen, X Ma, L Xie, W Chen, Z Xu, E Song, X Zhu… - Nanoscale, 2021 - pubs.rsc.org
Ferroptosis therapy, which applies ferroptotic inducers to produce lethal lipid peroxidation
and induce the death of tumor cells, is regarded as a promising therapeutic strategy for …
and induce the death of tumor cells, is regarded as a promising therapeutic strategy for …
Cell membrane camouflaged Metal Oxide–Black Phosphorus Biomimetic Nanocomplex enhances photo-chemo-dynamic ferroptosis
K Chen, H Li, A Zhou, X Zhou, Y Xu… - ACS Applied Materials …, 2022 - ACS Publications
Despite the availability of various treatment options, the inherent complexity of tumors
significantly impairs therapeutic efficacy. Recently, combination treatments exhibited great …
significantly impairs therapeutic efficacy. Recently, combination treatments exhibited great …
pH-activated nanoplatform for visualized photodynamic and ferroptosis synergistic therapy of tumors
R Sun, W Ma, M Ling, C Tang, M Zhong, J Dai… - Journal of Controlled …, 2022 - Elsevier
To overcome drug resistance and improve precision theranostics for hepatocellular
carcinoma (HCC), a nanoplatform with an “off/on” function for multimodality imaging (near …
carcinoma (HCC), a nanoplatform with an “off/on” function for multimodality imaging (near …
Biomimetic photosensitizer nanocrystals trigger enhanced ferroptosis for improving cancer treatment
M Wu, W Ling, J Wei, R Liao, H Sun, D Li… - Journal of Controlled …, 2022 - Elsevier
As a novel non-apoptotic cell death pathway, ferroptosis can effectively enhance the
antitumor effects of photodynamic therapy (PDT) by disrupting intracellular redox …
antitumor effects of photodynamic therapy (PDT) by disrupting intracellular redox …
[HTML][HTML] Ferroptosis promotes photodynamic therapy: supramolecular photosensitizer-inducer nanodrug for enhanced cancer treatment
The noninvasive nature of photodynamic therapy (PDT) enables the preservation of organ
function in cancer patients. However, PDT is impeded by hypoxia in the tumor …
function in cancer patients. However, PDT is impeded by hypoxia in the tumor …
Oxygen-boosted biomimetic nanoplatform for synergetic phototherapy/ferroptosis activation and reversal of immune-suppressed tumor microenvironment
Z He, H Zhou, Y Zhang, X Du, S Liu, J Ji, X Yang… - Biomaterials, 2022 - Elsevier
Photodynamic therapy (PDT) induces apoptosis of cancer cells by generating cytotoxic
reactive oxygen species, the therapeutic effect of which, however, is impeded by …
reactive oxygen species, the therapeutic effect of which, however, is impeded by …
Fenton reaction-assisted photodynamic therapy for cancer with multifunctional magnetic nanoparticles
H Hou, X Huang, G Wei, F Xu, Y Wang… - ACS applied materials …, 2019 - ACS Publications
Tumor hypoxia and the short half-life of reactive oxygen species (ROS) with small diffusion
distance have greatly limited the therapeutic effect of photodynamic therapy (PDT). Here, a …
distance have greatly limited the therapeutic effect of photodynamic therapy (PDT). Here, a …
Hypoxia-responsive nanoreactors based on self-enhanced photodynamic sensitization and triggered ferroptosis for cancer synergistic therapy
Background Photodynamic therapy (PDT), a typical reactive oxygen species (ROS)-
dependent treatment with high controllability, has emerged as an alternative cancer therapy …
dependent treatment with high controllability, has emerged as an alternative cancer therapy …
Lipid droplet targeting type I photosensitizer for ferroptosis via lipid peroxidation accumulation
T Xiong, Y Chen, Q Peng, S Lu, S Long, M Li… - Advanced …, 2024 - Wiley Online Library
As an iron‐dependent lipid peroxidation (LPO) mediated cell death pathway, ferroptosis
offers promises for anti‐tumor treatment. Photodynamic therapy (PDT) is an ideal way to …
offers promises for anti‐tumor treatment. Photodynamic therapy (PDT) is an ideal way to …