Immunometabolism is a burgeoning field dissecting the contribution of key metabolic
pathways to immune cell development, fate, and behavior. This SnapShot provides an …

Immune cells are highly dynamic in terms of their growth, proliferation, and effector functions
as they respond to immunological challenges. Different immune cells can adopt distinct …

Choices have consequences. Immune cells survey and migrate throughout the body and
sometimes take residence in niche environments with distinct communities of cells …

Metabolism is a core process underlying essentially all biological functions. The integration
of metabolism with immunity, known as immunometabolism, is at the forefront of immunology …

The immune response requires major changes to metabolic processes, and indeed, energy
metabolism and functional activation are fully integrated in immune cells to determine their …

Immunometabolism has emerged as a major mechanism central to adaptive and innate
immune regulation. From early observations that inflammatory cytokines were induced in …

In recent years a substantial number of findings have been made in the area of
immunometabolism, by which we mean the changes in intracellular metabolic pathways in …

Immune cell metabolism is dynamically regulated in parallel with the substantial changes in
cellular function that accompany immune cell activation. While these changes in metabolism …

Background Naïve lymphocytes circulate in the body in a resting state, but upon recognition
of foreign antigen and receipt of proper costimulatory signals, these cells become activated …

Studies of immune system metabolism (" immunometabolism") segregate along two paths.
The first investigates the effects of immune cells on organs that regulate whole-body …