Quantitative Assessment of Lung Microstructure in Healthy Mice using Lung Morphometry with Hyperpolarized 3He Diffusion MRI

E Osmanagic, AL Sukstanskii, JD Quirk… - Proc. Intl. Soc. Mag …, 2010 - archive.ismrm.org
Lung morphometry technique with hyperpolarized 3He allows quantification of lung
geometrical parameters such as mean chord length Lm, surface-to-volume ratio S/V and …

Quantitative assessment of lung microstructure in healthy mice using an MR-based 3He lung morphometry technique

E Osmanagic, AL Sukstanskii… - Journal of Applied …, 2010 - journals.physiology.org
The recently developed technique of lung morphometry using hyperpolarized 3He diffusion
magnetic resonance (MR)(Yablonskiy DA, Sukstanskii AL, Woods JC, Gierada DS, Quirk JD …

Imaging lung microstructure in mice with hyperpolarized 3He diffusion MRI

W Wang, NM Nguyen, DA Yablonskiy… - Magnetic resonance …, 2011 - Wiley Online Library
Quantitative measurement of lung microstructure is of great significance in assessment of
pulmonary disease, particularly in the earliest stages. The technique for MRI‐based 3He …

[PDF][PDF] Quantitative assessment of lung microstructure in

ER Conradi, DA Yablonskiy, E Osmanagic… - J Appl …, 2010 - researchgate.net
Osmanagic E, Sukstanskii AL, Quirk JD, Woods JC, Pierce RA, Conradi MS, Weibel ER,
Yablonskiy DA. Quantitative assessment of lung microstructure in healthy mice using an MR …

Probing lung microstructure with hyperpolarized 3He gradient echo MRI

AL Sukstanskii, JD Quirk, DA Yablonskiy - NMR in Biomedicine, 2014 - Wiley Online Library
In this paper we demonstrate that gradient echo MRI with hyperpolarized 3He gas can be
used for simultaneously extracting in vivo information about lung ventilation properties …

In Vivo Quantification Of Lung Morphometry In Healthy And Diseased Mice With Hyperpolarized 3he Diffusion MRI

JC Woods, W Wang, DA Yablonskiy… - A108. HOW USEFUL …, 2011 - atsjournals.org
Methods: 12-week-old C57BL/6 mice (n= 7) were anesthetized, mechanically ventilated on a
custom-built ventilator, and hyperpolarized 3 He diffusion MRI was performed at peak …

In vivo lung morphometry with hyperpolarized 3He diffusion MRI: theoretical background

AL Sukstanskii, DA Yablonskiy - Journal of magnetic resonance, 2008 - Elsevier
MRI-based study of 3He gas diffusion in lungs may provide important information on lung
microstructure. Lung acinar airways can be described in terms of cylinders covered with …

Optimal strategy for b-values selection for lung morphometry with hyperpolarized 3He diffusion MRI

AL Sukstanskii, JD Quirk, MS Conradi… - Proc. Intl. Soc. Mag …, 2009 - archive.ismrm.org
Lung morphometry with hyperpolarized 3He diffusion MRI allows estimation of lung
microstructural parameters. Herein Bayesian analysis is used to analyze how the accuracy …

Lung morphometry with hp gas diffusion MRI: from theoretical models to experimental measurements

DA Yablonskiy, AL Sukstanskii - Hyperpolarized and inert gas MRI, 2017 - Elsevier
Diffusion magnetic resonance imaging (MRI) is a unique tool that allows studying tissue
structure at a scale that is much smaller than experimentally achievable voxel resolution …

In vivo lung morphometry with accelerated hyperpolarized 3He diffusion MRI: A preliminary study

YV Chang, JD Quirk… - Magnetic resonance in …, 2015 - Wiley Online Library
Purpose Parallel imaging can be used to reduce imaging time and to increase the spatial
coverage in hyperpolarized gas magnetic resonance imaging of the lung. In this proof‐of …