Evolution of penicillin resistance in Streptococcus pneumoniae; the role of Streptococcus mitis in the formation of a low affinity PBP2B in S. pneumoniae
Penicillin‐resistant strains of Streptococcus pneumoniae possess forms of penicillin‐binding
proteins (PBPs) that have a low affinity for penicillin compared to those from penicillin …
proteins (PBPs) that have a low affinity for penicillin compared to those from penicillin …
Penicillin-resistant viridans streptococci have obtained altered penicillin-binding protein genes from penicillin-resistant strains of Streptococcus pneumoniae.
CG DowsON, A Hutchison… - Proceedings of the …, 1990 - National Acad Sciences
Penicillin-resistant strains of Streptococcus pneumoniae possess altered forms of penicillin-
binding proteins (PBPs) with decreased affinity for penicillin. The PBP2B genes of these …
binding proteins (PBPs) with decreased affinity for penicillin. The PBP2B genes of these …
Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae.
CG Dowson, A Hutchison… - Proceedings of the …, 1989 - National Acad Sciences
Resistance to penicillin in clinical isolates of Streptococcus pneumoniae has occurred by the
development of altered penicillin-binding proteins (PBPs) that have greatly decreased …
development of altered penicillin-binding proteins (PBPs) that have greatly decreased …
Genetics of high level penicillin resistance in clinical isolates of Streptococcus pneumoniae
VA Barcus, K Ghanekar, M Yeo, TJ Coffey… - FEMS microbiology …, 1995 - academic.oup.com
Mosaic penicillin-binding proteins (PBP) 1A, 2X and 2B genes were cloned from four clinical
isolates of Streptococcus pneumoniae with levels of susceptibility to penicillin ranging from …
isolates of Streptococcus pneumoniae with levels of susceptibility to penicillin ranging from …
Nucleotide sequences of the pbpX genes encoding the penicillin‐binding proteins 2x from Streptococcus pneumoniae R6 and a cefotaxime‐resistant mutant, C506
G Laible, R Hakenbeck, MA Sicard, B Joris… - Molecular …, 1989 - Wiley Online Library
Development of penicillin resistance in Streptococcus pneumoniae is due to successive
mutations in penicillin‐binding proteins (PBPs) which reduce their affinity for β‐lactam …
mutations in penicillin‐binding proteins (PBPs) which reduce their affinity for β‐lactam …
Interspecies recombinational events during the evolution of altered PBP 2x genes in penicillin‐resistant clinical isolates of Streptococcus pneumoniae
Penicillin resistance in pneumococci is due to the appearance of high molecular‐weight
penicillin‐binding proteins (PBPs) that have reduced affinity for the antibiotic. We have …
penicillin‐binding proteins (PBPs) that have reduced affinity for the antibiotic. We have …
Mosaic pbpX genes of major clones of penicillin‐resistant Streptococcus pneumoniae have evolved from pbpX genes of a penicillin‐sensitive Streptococcus oralis
C Sibold, J Henrichsen, A König, C Martin… - Molecular …, 1994 - Wiley Online Library
Penicillin‐resistant clinical isolates of Streptococcus pneumoniae contain mosaic penicillin‐
binding protein (PBP) genes that encode PBPs with decreased affinity for β‐lactam …
binding protein (PBP) genes that encode PBPs with decreased affinity for β‐lactam …
Alterations in penicillin-binding protein 2B from penicillin-resistant wild-type strains of Streptococcus pneumoniae
AM Smith, KP Klugman - Antimicrobial agents and chemotherapy, 1995 - Am Soc Microbiol
The 1.5-kb transpeptidase-encoding region (TER) of penicillin-binding protein (PBP) 2B was
amplified and sequenced from 18 penicillin-resistant isolates of Streptococcus pneumoniae …
amplified and sequenced from 18 penicillin-resistant isolates of Streptococcus pneumoniae …
Relatedness of penicillin‐binding protein 1a genes from different clones of penicillin‐resistant Streptococcus pneumoniae isolated in South Africa and Spain.
C Martin, C Sibold, R Hakenbeck - The EMBO Journal, 1992 - embopress.org
Penicillin‐resistant strains of Streptococcus pneumoniae have been common in South Africa
and Spain for several years. Multilocus enzyme electrophoresis identified one clone of …
and Spain for several years. Multilocus enzyme electrophoresis identified one clone of …
Deletion analysis of the essentiality of penicillin-binding proteins 1A, 2B and 2X of Streptococcus pneumoniae
An internal fragment from each of the penicillinebinding protein (PBP) 1A, 2B and 2X genes
of Streptococcus pneumoniae, which included the region encoding the active-site serine …
of Streptococcus pneumoniae, which included the region encoding the active-site serine …
相关搜索
- streptococcus mitis penicillin resistance
- streptococcus pneumoniae low affinity
- streptococcus pneumoniae binding proteins
- strains of streptococcus pneumoniae
- independent combinations low affinity
- clinical isolates of streptococcus pneumoniae
- streptococcus pneumoniae nucleotide sequences
- streptococcus pneumoniae independent combinations
- streptococcus pneumoniae pbpx genes
- streptococcus pneumoniae major clones
- streptococcus pneumoniae deletion analysis
- streptococcus pneumoniae horizontal transfer
- binding proteins pbpx genes
- binding proteins nucleotide sequences
- viridans streptococci protein genes
- streptococcus pneumoniae penicillin resistance