There is compelling evidence that nonsteroidal anti-inflammatory drugs (NSAIDs) and
cyclooxygenase-2 selective inhibitors have antineoplastic activity, but toxicity from …

Background Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to have
antitumor effects in various systems including in vitro cell cultures of human cancer cell lines …

Nonsteroidal anti-inflammatory drugs such as sulindac have shown promising antineoplastic
activity, although toxicity from cyclooxygenase (COX) inhibition and the suppression of …

Chemoprevention represents a highly promising approach for the control of cancer. That
nonsteroidal anti-inflammatory drugs (NSAIDs) prevent colon and other cancers has led to …

On the strength of in vitro, in vivo, observational, and clinical data, nonsteroidal
antiinflammatory drugs (NSAIDs)—also referred to as COX inhibitors—have emerged as …

Epidemiological and clinical studies suggest that non-steroidal anti-inflammatory drugs
(NSAIDs), including cyclooxygenase (COX)-2 selective inhibitors, reduce the risk of …

Non-steroidal anti-inflammatory drugs (NSAIDs) are used extensively for analgesic and
antipyretic treatments. In addition, NSAIDs reduce the risk and mortality to several cancers …

Nonsteroidal antiinflammatory drugs (NSAIDs) appear to reduce the risk of developing
cancer. One mechanism through which NSAIDs act to reduce carcinogenesis is to inhibit the …

NSAIDs (non-steroidal anti-inflammatory drugs) prevent colon and other cancers. The fact
that NSAIDs inhibit the eicosanoid pathway prompted mechanistic drug-developmental work …

Most solid tumors express the cyclooxygenase-2 (COX-2) protein, a target of NSAIDs. COX-
2 overexpression in tumorsis considered a predictor of more advanced stage disease and of …