Introduction A combination of genetic, environmental, and immunologic factors contributes to
the development of Multiple sclerosis (MS) disease. The IL23/Th17 pathway seems to play …

Vitamin D regulates gene expression and affects target cell functions. IL-6 and IL-17A are
pro-inflammatory cytokines associated with MS pathogenesis. The aim of this study was to …

Vitamin D deficiency is an environmental risk factor for MS, a Th17 cell-mediated
autoimmune disease that results in demyelination in the CNS. Therefore, we aimed to …

Background & aims In our previous study, a Seesaw model was proposed for the fluctuation
of crucial anti-(IL-10) and pro-inflammatory (Il-6 & IL-17A) cytokines through vitamin D3. In …

Background Vitamin D has immunomodulatory effects in multiple sclerosis (MS). Vitamin D
acts through various mechanisms such as secretion of cytokines. Interleukin-17 (IL-17) is a …

Objective To assess the effects of dietary vitamin D3 on proinflammatory (interleukin-17A [IL-
17A] and IL-6) and anti-inflammatory (IL-10) cytokines. Methods Our study was conducted …

Background During the last decade, vitamin D (VitD) has become a topic of interest in
immune regulation, especially in multiple sclerosis (MS) disease. Amongst the wide range of …

There is increasing evidence that vitamin D (VitD) supplementation may reduce
inflammation in individuals with multiple sclerosis (MS). The aim of this study was to …

Vitamin D is known to have immunomodulatory properties and its deficiency is identified as
an environmental risk factor for the development of autoimmune diseases, including multiple …

Multiple sclerosis (MS) is an inflammatory and autoimmune disease. Variety of different
genetics and environmental factors are involved in MS pathology. The epidemiological …