Association analyses for dopamine receptor gene polymorphisms and weight status in a longitudinal analysis in obese children before and after lifestyle intervention
Background Dopamine receptors are involved in midbrain reward circuit activation.
Polymorphisms in two dopamine receptor genes, DRD2 and DRD4, have been associated …
Polymorphisms in two dopamine receptor genes, DRD2 and DRD4, have been associated …
Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry
BACKGROUND: The biological mechanisms that link the development of depression to
metabolic disorders such as obesity and diabetes remain obscure. Dopamine-and plasticity …
metabolic disorders such as obesity and diabetes remain obscure. Dopamine-and plasticity …
Simultaneous absence of dopamine D1 and D2 receptor-mediated signaling is lethal in mice
M Kobayashi, C Iaccarino, A Saiardi… - Proceedings of the …, 2004 - National Acad Sciences
Dopamine (DA) controls a wide variety of physiological functions in the central nervous
system as well as in the neuroendocrine and gastrointestinal systems. DA signaling is …
system as well as in the neuroendocrine and gastrointestinal systems. DA signaling is …
Vitamin D3: a role in dopamine circuit regulation, diet-induced obesity, and drug consumption
JR Trinko, BB Land, WB Solecki, RJ Wickham… - Eneuro, 2016 - eneuro.org
The influence of micronutrients on dopamine systems is not well defined. Using mice, we
show a potential role for reduced dietary vitamin D3 (cholecalciferol) in promoting diet …
show a potential role for reduced dietary vitamin D3 (cholecalciferol) in promoting diet …
The role of dopamine in motivation for food in humans: implications for obesity
GJ Wang, ND Volkow, JS Fowler - Expert opinion on therapeutic …, 2002 - Taylor & Francis
Obesity is a major public health problem. The increasing number of obese individuals in the
US adds urgency to the efforts to understand the mechanisms underlying pathological …
US adds urgency to the efforts to understand the mechanisms underlying pathological …
Dopamine-based reward circuitry responsivity, genetics, and overeating
Data suggest that low levels of dopamine D2 receptors and attenuated responsivity of
dopamine-target regions to food intake is associated with increased eating and elevated …
dopamine-target regions to food intake is associated with increased eating and elevated …
Dopamine receptor D1 signaling stimulates lipolysis and browning of white adipocytes
J Yu, J Zhu, J Deng, J Shen, F Du, X Wu, Y Chen… - Biochemical and …, 2022 - Elsevier
Adipocytes express several kinds of catecholamine receptors, including adrenergic
receptors, and dopamine receptors. Signaling pathways mediated by catecholamine …
receptors, and dopamine receptors. Signaling pathways mediated by catecholamine …
Amelioration of binge eating by nucleus accumbens shell deep brain stimulation in mice involves D2 receptor modulation
CH Halpern, A Tekriwal, J Santollo… - Journal of …, 2013 - Soc Neuroscience
Hedonic overconsumption contributing to obesity involves altered activation within the
mesolimbic dopamine system. Dysregulation of dopamine signaling in the nucleus …
mesolimbic dopamine system. Dysregulation of dopamine signaling in the nucleus …
Obesity is associated with decreased μ-opioid but unaltered dopamine D2 receptor availability in the brain
Neurochemical pathways involved in pathological overeating and obesity are poorly
understood. Although previous studies have shown increased μ-opioid receptor (MOR) and …
understood. Although previous studies have shown increased μ-opioid receptor (MOR) and …
Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate
Methylphenidate (MP) is widely used to treat attention deficit hyperactivity disorder (ADHD).
Variable number of tandem repeats polymorphisms in the dopamine D4 receptor (D4) gene …
Variable number of tandem repeats polymorphisms in the dopamine D4 receptor (D4) gene …